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NEJM Examines Several Health Issues In Perspective Pieces
The New England Journal of Medicine published a series of perspectives that examine a variety of topics--from the struggle to finance health care reform to vaccine issues, the Food and Drug Administration and prescription drug marketing legislation in Vermont. The collection of perspectives includes a piece by Jonathan Gruber, PhD., "A Win-Win Approach to Financing Health Care Reform" and John K. Iglehart"s examination of Democrat"s challenge to securing money in "Finding Money for Health Care Reform - Rooting Out Waste, Fraud, and Abuse." Another piece, this one by Robert Steinbrook, M.D., examines new legislation in Vermont amid the background of reform of physician-industry relations in his piece "A Higher Bar - Vermont"s New Law on Marketing Prescribed Products."

New Invention To Fight Strokes
A revolutionary new device which could save the lives of stroke patients has been developed by a University of Wolverhampton expert.
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FDA Approves NovoLog(R) Labeling Update Increasing The Time Patients Can Use And Store NovoLog(R) In Their Pumps From Two Days To Six Days
Diabetes patients taking NovoLog® (insulin aspart [rDNA origin] injection) can now use the insulin in their pump for up to six days following the U.S. Food and Drug Administration (FDA) approval of a labeling change, diabetes care company Novo Nordisk announced today.[i] The previous label allowed for NovoLog® to be stored in the pump reservoir for two days. This makes NovoLog® the first and only rapid-acting insulin with this extended in-use time.
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A Group Of Proteins Highly Effective At Killing Bacteria And Which Could Hold The Key To Developing New Types Of Antibiotics To Be Studied

Researchers from the Universities of York and Leeds have been awarded ÷£3.3m from the Biotechnology and Biological Sciences Research Council (BBSRC) to find out how a family of proteins known as colicins force their way into bacterial cells before destroying them. The team, led by Professor Colin Kleanthous, from the University of York"s Department of Biology, will develop earlier research that suggests colicins use decoys to mimic key parts of the cells" own protein machinery to evade their defences. Professor Kleanthous said: "Colicins are the weapon used in the biological warfare that takes place between competing bacteria. Understanding how this group of proteins work could help scientists develop new drug delivery methods to target the bacteria that cause diseases in people." "It"s as though the colicins are carrying the equivalent of hand grenades which they can deploy without harming themselves," said Professor Sheena Radford of the University of Leeds" Faculty of Biological Sciences. The five year programme of research aims to discover how colicins specifically penetrate Gram-negative bacteria which are protected by two membrane barriers. It will involve collaboration between six groups of scientists from the Departments of Biology and Chemistry at the University of York and the Astbury Centre for Structural and Molecular Biology, Faculty of Biological Sciences, at the University of Leeds. James Reed University of York


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