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New HIV Cases Among Women In Wisconsin Increasing, Group Says
While the number of new cases of HIV in Wisconsin has stabilized over the last decade, women now represent more of the overall number of cases, the AP/Chicago Tribune reports (AP/Chicago Tribune, 6/2). According to Mike Gifford, CEO of the AIDS Re Center of Wisconsin (ARCW), 21 percent of new infections are women, compared with 16 percent in the 1990s and 6 percent in the1980s. Gifford says that women need to be better informed about their risk of contracting HIV. Christina Colon, ARCW"s associate director of prevention, said the organization is targeting women"s health fairs to raise awareness (Simonson, Wisconsin Public Radio, 6/1).

Senate Judiciary Committee Vote On Sotomayor Reset For July 28
The Senate Judiciary Committee on Tuesday postponed its vote on Supreme Court nominee Sonia Sotomayor until July 28 at the request of Republican members who said they need one more week to review written answers she recently submitted to the panel, CongressDaily reports. Both Republicans and Democrats expect Sotomayor to be approved by the committee and confirmed by the Senate, CongressDaily reports (CongressDaily, 7/21).The delay came as Senate Republicans continued to weigh whether they would vote to confirm Sotomayor, the Wall Street Journal reports. Sen. Susan Collins (R-Maine) announced plans to vote for Sotomayor and issued a statement calling the judge "committed to applying the law impartially without bias or favoritism." Four other moderate Republicans have said they will support Sotomayor, and Senate Judiciary Committee Chair Patrick Leahy (D-Vt.) indicated that more might follow suit. "There are a number of Republicans who have announced they plan to vote for her," Leahy said, adding, "There are a number of others who"ve not made that announcement yet, but plan to vote for her" (Peterson, Wall Street Journal, 7/21). Leahy said he is confident that Sotomayor will be confirmed in time for the Supreme Court"s first meeting on Sept. 9.Some strong conservatives, including Senate Minority Leader Mitch McConnell (Ky.), have said they will oppose Sotomayor (Hirschfeld Davis, AP/Denver Post, 7/22). Among the Senate Republicans who have not announced their intentions are Sens. John Cornyn (Texas), who serves on the Judiciary Committee, and Judd Gregg (N.H.) (Wall Street Journal, 7/21).NARAL Endorses Sotomayor NARAL ProChoice America recently said that it will endorse Sotomayor, the AP/Seattle Times reports. The group said that Sotomayor"s testimony shows that she is a stronger supporter of privacy rights than the last two Supreme Court nominees -- Chief Justice John Roberts and Justice Samuel Alito. Sotomayor said several times during her confirmation hearings that privacy rights include a woman"s right to have an abortion, NARAL said. According to the AP/Times, NARAL did not endorse Sotomayor until now because of uncertainty over her views on abortion rights (Hirschfeld Davis, AP/Seattle Times, 7/21).
News of the day
Burgess Response To President Obama's Answer To His Question On Medical Liability Reform
During today"s White House online town hall on health care, a question was submitted by Congressman Michael C. Burgess, M.D. (R-Texas), Chairman of the Congressional Health Care Caucus. Following President Obama"s response to the question on medical liability reform, Congressman Burgess issued the following statement:
Oncology

Automated 'Artificial Pancreas' Controls Blood Glucose Levels In Diabetes Patients For First Time

UC Santa Barbara and Sansum Diabetes Research Institute scientists have demonstrated for the first time that an automated artificial pancreas system (APS) can safely and effectively maintain desired blood glucose levels in patients with type 1 diabetes. The clinical study results will be presented today in a late-breaking poster session(1) at the American Diabetes Association"s 69th Scientific Sessions in New Orleans. The UCSB and Sansum researchers, working with the Schneider Children"s Medical Center of Israel, tested an automated insulin delivery system comprising the OmniPod(R) System and the DexCom STS7(R) continuous glucose monitor, linked and controlled through UCSB"s artificial pancreas software. The software"s insulin delivery algorithm, optimized for each patient, includes a unique safety feature, based on clinical parameters, which prevents insulin-induced low blood glucose levels (hypoglycemia). Without any outside intervention, the system restored normal blood glucose levels following both induced high levels (hyperglycemia) and unanticipated meals, while avoiding hypoglycemia. This was achieved through the automatic delivery of insulin to correct for the induced high blood glucose levels, and an insulin infusion rate moderated to ensure a smooth return to normal levels and avoid low blood glucose levels. "This study demonstrates for the first time a completely automated insulin delivery system that frees the patients from controlling their pumps manually, eliminating the question of compliance in treatment," said principal investigator Frank Doyle, Professor of Chemical Engineering at UCSB. Doyle continued, "We pulled together a talented team of engineers and medical doctors who created the critical element of the artificial pancreas--a unique algorithm that is robust and straightforward to implement. It"s become the gold standard." The UCSB APS software platform is also being used by a number of other teams working on the artificial pancreas project, but no other team has advanced yet to wholly-automated clinical trials. Closed loop trials were performed in four patients for a mean duration of 5 hours (range of 2-7 hours) and included a meal of 30 grams of carbohydrates. The mean Low Blood Glucose Index was 0.02 (range 0-0.06), the mean High Blood Glucose Index was 9 (range 4.2-15), and the median Daily Risk Range was "low" (range "low" to "moderate"). The poster was presented in New Orleans by Matthew Percival of Doyle"s research group. Other researchers in the study included Dr. Eyal Dassau, senior investigator, and Dr. Benyamin Grossman, both of Doyle"s group; and Sansum"s Dr. Lois Jovanovic, CEO and Chief Scientific Officer, and Dr. Howard Zisser, Director of Clinical Research. The research is part of the artificial pancreas project, which is funded by the Juvenile Diabetes Research Foundation and is being conducted by an international group of diabetes research centers. The project"s first goal is to integrate an insulin pump and continuous blood glucose monitor to closely replicate a healthy pancreas for patients with type 1 diabetes--patients whose pancreases no longer produce insulin, which is used by the body to control blood glucose levels. An artificial pancreas will allow for tighter and automated control of blood glucose levels, which would significantly help to avoid the long-term complications of the disease. UC Santa Barbara is a leading research institution. The two groups at UCSB involved in this study are the Department of Chemical Engineering, in 2007 ranked ninth in the United States and second in the University of California by U.S. News and World Report, and the Biomolecular Science and Engineering Program, which offers a unique interdisciplinary approach to graduate training and research spanning Biochemistry, Molecular Biology, Bioengineering and Biomolecular Materials. Sansum Diabetes Research Institute is a non-profit research center devoted to the prevention, treatment, and cure of diabetes through research and education. It is best known for its work on methods to detect and chart the progress of diabetes and its expertise in new diabetes technology. The OmniPod Insulin Management System--the OmniPod insulin pump and its Personal Diabetes Manager, which normally allows the patient to control it--is manufactured and sold by Insulet Corporation (Nasdaq: PODD). The DexCom STS7 continuous glucose monitor is a product of DexCom, Inc. (1) abstract 3-LB UC Santa Barbara Engineering


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