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Cardium Provides Update On Phase 2b Excellarate Clinical Study And Plans For Additional Tissue Repair Applications
Cardium Therapeutics (NYSE Amex: CXM) and its subsidiary Tissue Repair Company (TRC) provided an update on the completion of their MATRIX Phase 2b clinical study and announced plans to provide detailed safety and efficacy data for their Excellarate(TM) product candidate around the end of September. The MATRIX trial, a prospective, randomized, double-blind, placebo-controlled study, has enrolled 124 diabetic patients with non-healing, lower extremity neuropathic ulcers.

Anxiety And Depression Lower Quality Of Life In Majority Of Systemic Lupus Erythematosus Patients
92.8% of patients with systemic lupus erythematosus (SLE) suffer anxiety and depression which significantly affects both their physical and emotional quality of life (QoL), according to the results of a new study presented today at EULAR 2009, the Annual Congress of the European League Against Rheumatism in Copenhagen, Denmark. Logistic regression analysis revealed that depression was the most significant factor shown to affect QoL (p=0.015; OR=0.18; CI 95%:0.045-0.72).
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State Psychiatric Technicians Ask Californians To 'Support Our Services'
The California Association of Psychiatric Technicians will begin informational pickets next Wednesday at state hospitals, developmental centers and prisons, drawing attention to ongoing cuts that are not only hurting employees, but also the vital services Psych Techs provide to Californians in their care.
Mental Health

Discarded Fallopian Tubes Could Be Rich Of Stem Cells, Study

Fallopian tubes normally discarded after hysterectomies and other procedures could become rich potential s for mesenchymal stem cells which like other types of stem cell can be coaxed to develop into a variety of cell types, according to a new study by researchers in Brazil. Researchers from the University of Sç£o Paulo"s Human Genome Research Centre, which is directed by Dr Mayana Zatz conducted the study in collaboration with medical doctors from the University"s reproductive surgery department. The results are published as an online paper in BioMed Central"s open access Journal of Translational Medicine. The authors wrote that scientists have already discovered that umbilical cords, dental pulp and fat tissue, which they described as "biological discards", yield mesenchymal stem cells that can develop into muscle, fat, bone and cartilage tissue. This prompted them and other teams to look for more s, since stem cells obtained this way don"t raise the ethical problems that occur when stem cells are taken from embryos. As first author Tatiana Jazedje noted in a separate statement: "Use of human tissue fragments that are usually discarded in surgical procedures does not pose ethical problems." In this study the Brazilian team used fallopian tubes obtained from hysterectomy and other gynecological procedures undergone by fertile women aged from 35 to 55 who had been clear of any hormone treatments for at least three months beforehand. After isolating mesenchymal stem cells from the fallopian tubes, the researchers found that they were quite easy to expand in vitro where they differentiated readily into muscle, fat, cartilage and bone cell lines. The researchers found no abnormality in the chromosomes of the new cell lines, suggesting they had good chromosomal stability. They concluded that: "Human tube MSCs [mesenchymal stem cells] can be easily isolated, expanded in vitro, present a mesenchymal profile and are able to differentiate into muscle, fat, cartilage and bone in vitro. " Jazedje said that as well suggesting a possible new of stem cells for regenerative treatments, their findings will hopefully help reproductive science as a whole. "Human fallopian tube: a new of multipotent adult mesenchymal stem cells discarded in surgical procedures." Tatiana Jazedje, Paulo M Perin, Carlos E Czeresnia, Mariangela Maluf, Silvio Halpern, Mariane Secco, Daniela F Bueno, Natassia M Vieira, Eder Zucconi, Mayana Zatz. Journal of Translational Medicine 2009, 7:46. Published online 18 June 2009. doi:10.1186/1479-5876-7-46 BioMed Central. Written by: Catharine Paddock, PhD Copyright: Medical News Today Not to be reproduced without permission of Medical News Today


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