Popular Articles

DeCODE-led Megastudy Finds New Genetic Clues To Causes Of Schizophrenia
The largest study of the genetics of schizophrenia ever undertaken has revealed several new common single-letter variants in the sequence of the human genome (SNPs) linked to risk of the disease. The study, by a multinational consortium of scientists led by a team from deCODE genetics (Nasdaq: DCGN), analyzed the genomes of more than 50,000 patients and control participants from fourteen countries. It is published today in the online edition of Nature.

Care Management Reduces Depression And Suicidal Thoughts In Older Primary Care Patients
Depression in older adults too often goes unrecognized and untreated, resulting in untold misery, worsening of medical illness, and early death. A new study has identified one important remedy: Adding a trained depression care manager to primary care practices can increase the number of patients receiving treatment, lead to a higher remission rate of depression, and reduce suicidal thoughts.
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A Novel Approach For Treating Cognitive Impairments Identified By Animal Model For Schizophrenia
Researchers have been seeking a safe and effective way to treat cognitive impairments associated with schizophrenia by enhancing N-methyl-D-aspartate (NMDA) glutamate receptors. Functional deficits in NMDA receptors may contribute to the underlying neurobiology of this disorder. The first generation of studies trying to stimulate NMDA receptors administered large amounts of substances, like glycine or D-serine, which indirectly enhance NMDA receptor function. While there were some positive reports of efficacy, findings across studies were more inconsistent than was hoped.
Endocrinology

Dying At Home: A Trend That Could Make Hospitals More Efficient

Hospitals across Canada are seeking ways to free up beds. University of Alberta researcher Donna Wilson has a suggestion: people should be encouraged to die at home rather than in hospital. She looked at statistics dating back to 1950 and has found that there"s been a dramatic change in the location of death of Canadians. Up until 1994, about 80 per cent of people dying each year were passing on in hospital. Now that number is down to 61 per cent, and Wilson is hoping the trend continues. She"d like to see only 40 per cent of people passing on in hospital because, with an aging baby boom population, this could reduce wait lists and free up hospital beds for those who need life-saving treatment or surgery. In most cases, she says, it"s also a much more dignified death for a family member. Wilson says in the next 20 years the number of people dying could double and if death rates in hospital stay at 80 per cent. those numbers mean a potential tie-up of every single bed in Canada for three days of the year, because each person takes up a bed for an average of 10 days. The professor in the Faculty of Nursing wants to see governments put more money into developing hospices, nursing homes and training for home care. Quinn Phillips University of Alberta


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