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New Informa Healthcare Web Site Now Live - Site Features More Than 180 Peer-Reviewed Journals
Informa Healthcare - one of the world"s leading medical and scientific publishers- has announced that the new interactive http://www.informahealthcare.com site is now live and delivers online content from more than 180 peer-reviewed journals.

Case For Preventive Prostate Cancer Treatment Bolstered By Stanford Study
For the last six years, doctors have faced a dilemma about whether to treat men at risk of prostate cancer with the drug finasteride. On one hand, the drug had been shown to prevent cancer in about one of every four patients who received it. On the other, those who did develop cancer while on the drug were 25 percent more likely to have a more aggressive form of the disease.
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Women At Risk Of Gaining Excessive Weight With Injectable Birth Control Identified By UTMB Study
Researchers at the University of Texas Medical Branch at Galveston have identified women who are likely to gain weight while using depot medroxyprogesterone acetate, more commonly known as Depo-Provera or the birth control shot. These findings dispel the myth that all women who use DMPA will gain weight and will help physicians to counsel patients appropriately.
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Fatness In Blacks Overestimated By Widely Used Body Fat Measurements

The body mass index (BMI) and waistline measurement overestimate obesity in blacks, according to a new study. The results, which were presented at The Endocrine Society"s 91st Annual Meeting in Washington, D.C., suggest that conventional methods for estimating body fat may need to become race-specific. "Compared to Caucasians, African-Americans of the same age, gender, waist circumference, weight and height may have lower total and abdominal fat mass," said principal investigator and study leader Samuel Dagogo-Jack, MD, professor of medicine and chief, Division of Endocrinology, Diabetes and Metabolism, University of Tennessee Health Science Center, Memphis. "These findings argue for a review of the existing cutoffs for healthy BMI and waist circumference among African-Americans." BMI is a simple and common method of estimating someone"s body fat levels, based on that person"s weight and height measurement. Obesity experts classify an adult who has a BMI less than 18.5 as underweight; normal weight is 18.5 to 24.9, overweight is 25 to 29.9 and obese is more than 30. An indirect measurement, BMI is not a reliable indicator of body fat for people who have a large body frame or lots of lean muscle. More specialized methods, such as DEXA bone density scanning or computed tomography (CT), can directly measure total and regional body fat, but these methods are expensive and more time-consuming. The waist circumference is used to identify abdominal obesity. This fat around the middle carries a higher risk for obesity-related complications such as diabetes and heart disease. Experts define abdominal obesity as a waist circumference greater than 40 inches in men and more than 35 inches in nonpregnant women. National data show that blacks have higher rates of obesity and type 2 diabetes than whites. Dagogo-Jack and his co-workers therefore examined whether the relationship between body fat and BMI would differ by race. In a study funded by the National Institutes of Health and the American Diabetes Association, they compared how close BMI was to body fat directly measured by DEXA in whites and blacks. The researchers performed the same comparison for waist circumference and abdominal fat. They studied 93 nondiabetic adults (53 blacks and 40 whites) who have one or both parents with type 2 diabetes. Subjects had a broad range of body weights. The correlation between DEXA-measured total fat and the BMI was higher in whites than blacks, the authors reported. The same was true for the correlation between directly measured abdominal fat and waist size. Therefore, body fat is likely to be lower in blacks than in whites of the same weight and height, Dagogo-Jack said. He said their data suggest that muscle mass may be higher in blacks, which would explain the dissociation between weight expressed as BMI and measured body fat. "If our results are confirmed in a larger study population by other researchers, the obesity field will need to develop ethnic-specific cutoffs for what values represent overweight and obesity," he concluded. Aaron Lohr The Endocrine Society


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