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Innovative Medicines Initiative Provides 246 Million Euros To Support Public-private Research Cooperation For The Faster Development Of Innovative Med
Today, fifteen new research projects aimed at bringing innovative medicines to market faster have been selected to receive 246 million Euros from the European Commission and the European Federation of Pharmaceutical Industries and Associations (EFPIA), of which the Irish Pharmaceutical Healthcare Association (IPHA) is a member. The projects will foster understanding of health issues such as diabetes, pain, severe asthma and psychiatric disorders while increasing medicine safety. They will also help improve the training of researchers and clinicians involved in medicines development. The projects were chosen following the first call for proposals launched within the Innovative Medicines Initiative (IMI), a public-private partnership - so called Joint Technology Initiative - between the European Commission and the pharmaceutical industry.

New Study Shows Nexium 40 Mg And 20 Mg Reduced Gastric And Duodenal Ulcers By 80 - 85% In Patients Taking Low-Dose Aspirin For CV Protection
Esomeprazole significantly reduced the occurrence of gastric and duodenal ulcers and upper gastrointestinal (GI) symptoms in patients taking low-dose aspirin for risk reduction of adverse cardiovascular (CV) events[i], such as myocardial infarction (MI) and ischaemic stroke, according to new data presented today at the Digestive Diseases Week annual meeting (DDW, 30thMay - 4th June, Chicago).
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A Novel Approach For Treating Cognitive Impairments Identified By Animal Model For Schizophrenia
Researchers have been seeking a safe and effective way to treat cognitive impairments associated with schizophrenia by enhancing N-methyl-D-aspartate (NMDA) glutamate receptors. Functional deficits in NMDA receptors may contribute to the underlying neurobiology of this disorder. The first generation of studies trying to stimulate NMDA receptors administered large amounts of substances, like glycine or D-serine, which indirectly enhance NMDA receptor function. While there were some positive reports of efficacy, findings across studies were more inconsistent than was hoped.
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Fish Poisoning May Be Why Polynesians Left Paradise

Ciguatera poisoning, the food-borne disease that can come from eating large, carnivorous reef fish, causes vomiting, headaches, and a burning sensation upon contact with cold surfaces. An early morning walk on cool beach sand can become a painful stroll on fiery coals to a ciguatera victim. But is this common toxin poisoning also the key to a larger mystery? That is, the storied migrations of the Polynesian natives who colonized New Zealand, Easter Island and, possibly, Hawaii in the 11th to 15th centuries? Could ciguatera be the reason masses of people left paradise? Teina Rongo, a Cook Island Maori from Rarotonga and a Ph.D. student at the Florida Institute of Technology, and his faculty advisers Professors Robert van Woesik and Mark Bush, propose this intriguing theory in an upcoming issue of the Journal of Biogeography. Based on archeological evidence, paleoclimatic data and modern reports of ciguatera poisoning, they theorize that ciguatera outbreaks were linked to climate and that the consequent outbreaks prompted historical migrations of Polynesians. Why would historic populations of Cook Islanders take the chance of voyaging? A journey beyond the horizon was risky and favorable landfalls were uncertain. It is known that this population was heavily reliant on fish as a of protein, and the scientists suggest that once their fish res became inedible, voyaging became a necessity. Modern Cook Islanders, though surrounded by an ocean teeming with fish, don"t eat fish as a regular part of their diet but instead eat processed, imported foods. In the late 1990s, lower-income families who could not afford processed foods emigrated to New Zealand and Australia. The researchers suggest that past migrations had similar roots. The heightened voyaging from A.D. 1000 to 1450 in eastern Polynesia was likely prompted by ciguatera fish poisoning. There were few options but to leave once the staple diet of an island nation became poisonous. "Our approach brings us a step closer to solving the mysteries of ciguatera and the storied Polynesian native migrations. We hope it will lead to better forecasting and planning for ciguatera outbreaks" says van Woesik. Karen Rhine Florida Institute of Technology


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