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Prevention Program Helps Teens Override A Gene Linked To Risky Behavior
A family-based prevention program designed to help adolescents avoid substance use and other risky behavior proved especially effective for a group of young teens with a genetic risk factor contributing toward such behavior, according to a new study by researchers at the University of Georgia. The National Institute on Alcohol Abuse and Alcoholism (NIAAA) and the National Institute on Drug Abuse (NIDA), components of the National Institutes of Health, supported the study, which appears in the May/June issue of Child Development.

Advaxis Receives FDA Response To Orphan Drug Filing
Advaxis, Inc. (OTCBB:ADXS) received the FDA letter late on June 1 denying the company"s request for Orphan Drug Designation (ODD) for the use of ADXS11-001 in invasive cervix cancer. The FDA stated their market definition for invasive cervical cancer prevalence (including all those who had been cured) is over the 200,000 person cutoff. Further, the applicability of ADXS11-01 for a precursor condition, cervical intraepithelial neoplasia (CIN) was considered by the ODD as an early manifestation of the disease. No prevalence estimate for CIN was provided in our original application. There was no issue raised about efficacy.
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Secondary Prevention: Aspirin Combined With Dipyridamole Just As Effective As Clopidogrel; Endarterectomy Safer Than Angioplasty
In the area of secondary prevention as well - guarding against renewed events in patients who already suffered from a stroke or a TIA - Professor Ferro points to important new research: "In this patient population, the direct comparison between Clopidogrel and the combination of aspirin with extended release Dipyridamole did not reveal any difference between both strategies." Both approaches have proven to be slightly more effective than aspirin alone.
Oncology

Industry Leaders Offer Solutions For Health Care Reform

The Chicago Tribune published a series of articles on industry"s solutions for health care reform. The paper "turned to Chicago-area leaders in three key segments of the industry: insurers, medical providers and pharmacy," and presented their "thoughts on how best to expand medical-care coverage to all Americans." Pharmacists: "By helping patients make better choices, pharmacists say they can help save billions." But for "medication therapy management" to be effective, they"ll need higher payments. This article was highlighted in yesterday"s edition of the Kaiser Daily Report. Insurers: Blue Cross and Blue Shield of Illinois president Paul Boulis says that for a health care expansion to be successful, "all consumers need to be enrolled in a plan." Without a mandate, "consumers could defer getting coverage until they need medical care, and that can lead to higher premium costs for those with insurance." Mandated coverage allows insurers to "spread the risk" and provides them with a larger pool of money to help them pay for claims, which "helps them turn a profit and provide benefits and services to more people." Boulis says the recession has been bad for business. "For the first time in a quarter century," Blue Cross and Blue Shield expects enrollment to drop this year. A mandate would "get everybody under the umbrella," Boulis says, but he says that doesn"t necessarily mean costs will level off. "He worries about the millions of people who may have been avoiding the doctor"s office or ignoring their ailments flocking to the health-care system. "A good portion of those people are going to have myriad problems," he said. "You are going to have to be very savvy about what you cover."" But numerous health plans, including Blue Cross, has told Congress they "would not reject coverage for consumers with pre-existing medical conditions" if a mandate is included in the overhaul. Doctors: For health reform to be effective, doctors in small practices must get "funds and support to equip their offices with the latest technology and quality data," says Dr. Lee Sacks, the "top administrative physician at the largest provider of medical care in Chicago." "Most Americans receive their care from practices of fewer than five doctors," and those doctors complain of "lack of infrastructure to effectively address future patient needs." Sacks" provider organization, Advocate Health Care, lends "res to the more than 3,200 independent doctors, largely in small practices" who are trying to improve their quality of care. He says that organizing small practices is needed to "effectively implement health-care reform that is high-quality and cost-effective." Some of the assistance, Sacks says, "is coaching and training, and some of that is infrastructure, data and feedback," including electronic health records. He expects additional money will be needed to "offset the additional coverage" (Japsen, 6/4). This information was reprinted from kaiserhealthnews.org with kind permission from the Henry J. Kaiser Family Foundation. You can view the entire Kaiser Daily Health Policy Report, search the archives and sign up for email delivery at kaiserhealthnews.org. © Henry J. Kaiser Family Foundation. All rights reserved.


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