Popular Articles

Lupus Foundation Of America Seeks Proposals For Research Studies On Childhood Lupus And Stem Cell Transplantation
The Lupus Foundation of America (LFA) is seeking proposals for grant funding for research studies on lupus, an unpredictable and potentially fatal autoimmune disease. Grants will support areas of study in pediatric lupus and adult stem cell transplantation. The purposes of the studies are to advance adult stem cell transplantation research in humans as a treatment for lupus and address key understanding of pediatric/adolescent lupus research issues.

Obama Issues Directive To Enact New Embryonic Stem Cell Research Rules
President Obama on Thursday issued a directive to federal agencies to begin following new NIH guidelines on federally funded embryonic stem cell research, Reuters/New York Times reports (Reuters/New York Times, 7/30). NIH announced the final guidelines earlier this month. The guidelines assess whether newly created embryonic stem cell lines can be used for federally funded research, as well as clarify how old lines will be evaluated (Daily Women"s Health Policy Report, 7/7).In March, Obama overturned President George W. Bush"s policy limiting federal funding of embryonic stem cell research. In a statement Thursday, Obama said, "I hereby direct the heads of executive departments and agencies that support and conduct stem cell research to adopt these guidelines, to the fullest extent practicable in light of legal authorities and obligations" (Reuters/New York Times, 7/30).
News of the day
Innovative Treatment Approach Offers New Hope For Eczema Sufferers With Moderate To Severe Disease PROTOPIC Ointment Can Help Prevent Eczema Flares
Today sees the European launch of the first topical calcineurin inhibitor to be approved for the maintenance treatment of eczema to prevent flares and prolong flare-free intervals. PROTOPIC ointment (tacrolimus monohydrate) is already licensed to treat moderate and severe eczema (atopic dermatitis), often involving the treatment of flares as and when they occur.* It is now also approved for twice-weekly application to previously affected skin to prevent these exacerbations and prolong flare-free periods in PROTOPIC-responsive patients.ò€  Clinical studies have shown that this new approach brings significant benefits with over 40% of patients with moderate to severe eczema remaining flare-free for at least a year.1 Flares are known to place an enormous burden on patients. The International Study of Life with Atopic Eczema (ISOLATE) found that about 55% of these patients worried about the onset of their next exacerbation and that they spent on average over a third of the year (136 days) with their eczema in flare.2
Endocrinology

Vehicle Designed For Blind To Take The Wheel

A student team in the Virginia Tech College of Engineering is providing the blind with an opportunity many never thought possible: The opportunity to drive. A retrofitted four-wheel dirt buggy developed by the Blind Driver Challenge team from Virginia Tech"s Robotics and Mechanisms Laboratory uses laser range finders, an instant voice command interface and a host of other innovative, cutting-edge technology to guide blind drivers as they steer, brake, and accelerate. Although in the early testing stage, the National Federation of the Blind -- which spurred the project -- considers the vehicle a major breakthrough for independent living of the visually impaired. "It was great!" said Wes Majerus, of Baltimore, the first blind person to drive the buggy on a closed course at the Virginia Tech campus this summer. Majerus is an access technology specialist with the National Federation of the Blind"s Jernigan Institute in Baltimore, a research and training institute dedicated to developing technologies and services to help the blind achieve independence. Majerus called his drive a liberating experience, adding that he drove before on Nebraska farm roads with his father as a guide in the passenger seat. Sitting inside the vehicle, a blind driver can turn the steering wheel, stop and accelerate by following data from a computing unit that uses sensory information from the laser range finder serving as the "eyes" of the driver, in addition to a combination of voice commands and a vibrating vest as guides. A member of the Virginia Tech student team sat next to Majerus in the passenger seat to monitor the system"s software operations. "It"s a great first step," Majerus added. "As far as the differences between human instructions and those given by the voice in the Blind Driver Challenge car, the car"s instructions are very precise. You use the technology to act on the environment -- the driving course -- in a very orderly manner. In some cases, the human passenger will be vague, "turn left" -- does that mean just a small turn to the left, or are we going for large amounts of turn?" Also driving the vehicle was Mark Riccobono, also of Baltimore, the executive director of the Jernigan Institute, who also is blind. He called his test drive historic. "This is sort of our going to the moon project," he said In 2004 Jernigan Institute challenged university research teams to develop a vehicle that would one day allow the blind to drive. Virginia Tech was the only university in the nation to accept the nonprofit"s call two years later, said Dennis Hong, director of the Robotics and Mechanisms Laboratory, part of the Virginia Tech mechanical engineering department. The National Federation of the Blind provided a $3,000 grant to launch the project. "I thought it would be a very rewarding project, helping the blind," said Hong, the current faculty adviser on the project. "We are not only excited about the vehicle itself, but more than that, we are excited about the potential of the many spin-off technologies from this project that can be used for helping the blind in so many ways." The team will bring the Blind Driver Challenge vehicle to the National Federation of the Blind"s Youth Slam summer camp event held July 26 through Aug. 1 in College Park, Md. There, the team hopes to have teenagers who would be obtaining their driver"s licenses, but cannot because of their blindness, drive the buggy. Youth participants also are expected to remote control drive miniature cars. Additionally, the car is expected to ride in a National Federation of the Blind-sponsored parade in Washington D.C. "I most look forward to learning as much as I can from these bright young students," said Greg Jannaman, who led the Virginia Tech student team in his senior year and graduated in May with a bachelor"s degree in mechanical engineering. "Blind students from across the nation apply to be selected to attend this summer camp. While we are there to provide an educational experience for them, I can only imagine the invaluable feedback and fresh new ideas that they will provide in return." Jannaman is excited about the vehicle"s success. "There wasn"t a moment"s hesitation with any of our blind drivers, whereas blind-folded sighted drivers weren"t as quick to let go of their preconceptions," said Jannaman of Hendersonville, Tenn. "The blind drivers actually performed better than their sighted counterparts. An overwhelming sense of accomplishment overcame me as I simply rode along while Wes and Mark successfully navigated the driving course without my assistance." Early models of the Blind Driver Challenge vehicle relied more on technologies for fully autonomous vehicles, previously developed by Virginia Tech mechanical engineering students as part of the DARPA Urban Challenge. The student team redesigned the vehicle so that the blind motorist has complete control of the driving process, as any sighted driver would. This change in approach led to new challenges, including how to effectively convey the high bandwidth of information from the laser sensors scanning the vehicle"s surrounding environment to the driver fast enough and accurate enough to allow safe driving. As a result, the team developed non-visual interface technologies, including a vibrating vest for feedback on speed, a click counter steering wheel with audio cues, spoken commands for directional feedback, and a unique tactile map interface that utilizes compressed air to provide information about the road and obstacles surrounding the vehicle. Riccobono knows of mock ups and non-working "blind driver car" set-ups from the past, but says this is the first working vehicle to put the blind and visually impaired in control of the steering wheel. "Blind people have brains, the capacity to make decisions," he said. "Blind people want to live independent lives, why would they not want to drive?" Even once the technology is perfected, laws now barring the blind from driving and public perception must be changed, Riccobono said. "This is the piece that we know will be the most difficult," said Riccobono, adding that the car must be near-perfected before the National Federation of the Blind can truly push the car to law-makers and the general public. He said this effort will take millions of dollars in development. The 2009-10 student team already is planning major changes to the technology, including replacing the dirt buggy vehicle with a fully electric car commonly used by traffic officers in downtown city centers. The all-electric vehicle would reduce the vibration which can cause problems to the laser sensor, and it will provide clean electric power for the computing units and that is better for the environment. Steven Mackay Virginia Tech


Add your comment:
Name:
Site address: http://
Your message:
Enter today\\\\'s date, 2 digits
(spam protection):