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Small Clinical Trial Examines Drug's Ability To Reduce HIV In Body
In the first human trial of GlaxoSmithKline"s (GSK) experimental HIV drug S/GSK1349572, the drug was able to reduce HIV to undetectable levels in 70 percent of the 35 patients taking the treatment for 10 days, according to findings presented at the International AIDS Society"s conference in Cape Town, South Africa, Bloomberg reports. The drug decreased the virus in the body "without the signs of resistance linked to treatments from" Merck"s Isentress and Gilead Sciences" Elvitegravir, according to Bloomberg. GSK will begin a larger trial of the drug this month, Sherene Min, the director of clinical pharmacology discovery medicine for GSK, said. Michael Saag, director of the Center for AIDS Research at the University of Alabama, who is not affiliated with the study, said the scale of viral reduction was "spectacular," adding, "In 10 days to go to undetectable is pretty strong. This thing"s working" (Bennett, 7/21).
weight loss
2009 Dr. Paul Janssen Award For Biomedical Research Won By Axel Ullrich
Johnson & Johnson has announced that Axel Ullrich, Ph.D., director of the Department of Molecular Biology at the Max Planck Institute of Biochemistry in Germany, whose discoveries have led to novel cancer therapies including Herceptin® (trastuzumab) , is the winner of the 2009 Dr. Paul Janssen Award for Biomedical Research. An independent committee of world-renowned scientists selected Dr. Ullrich, who on September 8 will receive a $100,000 prize during a ceremony in Beerse, Belgium.
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The Bazelon Center Welcomes President Obama's Pledge To People With Mental Disabilities On Olmstead's 10th Anniversary
The Bazelon Center for Mental Health Law welcomes President Obama"s announcement today of his commitment to the promise of the landmark Supreme Court case, Olmstead v. L.C., on its 10th anniversary. In a statement released by the White House today the President launched a "Year of Community Living" and tasked the Departments of Health and Human Services (HHS) and Housing and Urban Development (HUD) to identify initiatives that will develop and improve services and supports to assist people with disabilities who wish to live in the most integrated settings possible.

Endocrinology

Health Canada Confirms No Health Risk From BPA In Baby Food, Powdered Infant Formula, And Bottled Water

As part of its research commitment on bisphenol A (BPA), Health Canada released yesterday the results of studies investigating BPA exposure levels in baby food in glass jars with metal lids, powdered infant formula, and bottled water. The results from these three government studies provide definitive confirmation that baby food products packaged in glass jars with metal lids, powdered infant formula, and bottled water do not pose a health risk. Researchers found that all levels of BPA found in tested products were exceedingly low and all are well below the level established as safe for consumers by the Canadian government. The North American Metal Packaging Alliance, Inc. (NAMPA) welcomes the latest Canadian study, noting that these findings confirm industry"s own research that shows BPA levels in food containers are negligible.

Summer\'s Here: HSE Won\'t Rain On Your Paradeò€¦or Your Fete!

If you believe everything you read, "health and safety" is to blame for a lot of fun events being cancelled. Plastic duck races, ice cream toppings and even Morris Dancing have all allegedly fallen victim to excessive health and safety regulations.

Extreme Sports Not About Risk-taking: Study

Those who think extreme sports are all about risk-taking are missing the point, according to a QUT researcher. Eric Brymer, a lecturer from the School of Human Movement Studies in the Faculty of Health, has been researching whether the element of risk was an important factor among participants in "extreme" sports such as waterfall kayakers, mountain climbers, big wave surfers and B.A.S.E. jumpers.

(Pet) Food For Thought Getting To The Bottom Of The Business

The world of pet food can be a dizzying place. Who makes what? Is the industry regulated? What information is - and isn"t - included on pet food labels? Have things changed at all since the massive pet food recall in 2007?

When A Dog Bites

A pet bites a child, and the owner is faced with an excruciating decision: Is it safe to keep this dog?

Bayer Presents Positive Phase II Data With Florbetaben Potential To Visualize Beta-Amyloid Plaques In Patients With Alzheimer\'s Disease

Bayer Schering Pharma

Easy Strength Training Exercise May Help Treat Tennis Elbow, Study Shows

People with pain in the elbow or forearm from playing sports or just from common

Inovio Biomedical H1N1 Influenza DNA Vaccines Demonstrate 100% Responses Against Swine Flu In Vaccinated Pigs

Inovio Biomedical Corporation (NYSE Amex:INO), a leader in DNA vaccine design, development and delivery, announced today that the company"s SynCon™ H1N1 influenza DNA vaccines achieved protective antibody responses against H1N1 swine influenza virus (A/Swine/Iowa/35233/1999) in 100% of pigs immunized with a two-dose vaccine regimen.

Texas Department Of State Health Services Issues Fish Advisory For Clear Creek

The Texas Department of State Health Services has issued an advisory warning people not to consume any species of fish from Clear Creek. The creek runs through parts of Brazoria, Fort Bend, Galveston and Harris counties. The advisory was issued after laboratory testing showed elevated levels of polychlorinated biphenyls, or PCBs, in fish samples collected from the creek.

Women\'s Way Expands Mammography Services To Eligible Women In Their 40s, North Dakota, USA

Women"s Way, North Dakota"s breast and cervical cancer early detection

FDA Takes Enforcement Action Against Three New Jersey Dietary Supplement And Protein Powder Manufacturers

The U.S. Department of Justice, on behalf of the U.S. Food and Drug Administration, has filed a complaint for permanent injunction against Quality Formulation Laboratories, Inc., American Sports Nutrition Inc., Sports Nutrition International LLC and Mohamed S. Desoky, who oversees operations at all three companies.

What Are Menstrual Cramps? What Causes Menstrual Cramps? What Are Period Pains?

Menstrual cramps, also known as dysmenorrhea or period pains, are painful sensations felt in the lower abdomen that can occur both before and during a woman"s menstrual period. The pain ranges from dull and annoying to severe and extreme. Menstrual cramps tend to begin after an egg is released from the ovaries and travels down the fallopian tube (ovulation).

Patient Enrollment Complete For Phase I/II Clinical Trial For GALNS For Morquio A Syndrome

BioMarin Pharmaceutical Inc. (Nasdaq: BMRN) announced that patient enrollment has been completed for the Phase I/II clinical trial for BMN-110 or N-acetylgalactosamine 6-sulfatase (GALNS), intended for the treatment of the lysosomal storage disorder Mucopolysaccharidosis Type IVA (MPS IVA), or Morquio A Syndrome. The company expects to report initial results in the first half of 2010.

Fremont Patients, Public Health Endangered By Kaiser Cutbacks In Urgent Services

TUESDAY: Dozens of Registered Nurses to March on Kaiser Permanente-Fremont to Protest Effort to Slash Urgent Care

Growth Factor May Explain Why African-Americans Are At Greater Risk Of Hypertension And Kidney Disease

Physician-scientists from NewYork-Presbyterian Hospital/Weill Cornell Medical Center believe that a heightened level a certain growth factor in the blood may explain why blacks have a greater prevalence of hypertension and kidney disease compared to whites. Results from a new study are the first to show that an elevated level of a protein, called transforming growth factor B1 (TGF-B1), raises the risk of hypertension and renal disease in humans.

Dietitians Urge Health Ministers To Adopt A National Framework For Home Enteral Nutrition, Australia

Governments could be saving up to $7.88 million a year if they adopt a national home enteral

White Matter Changes May Predict Dementia Risk

Elderly people with no memory or thinking problems are more likely to later develop thinking problems if they have a growing amount of "brain rust," or small areas of brain damage, according to a study published in the July 14, 2009, print issue of Neurology®, the medical journal of the American Academy of Neurology.

People Who Bike Or Walk To Work Are More Fit, Less Fat Than Drivers

Trying to get fit but can"t work it into your daily schedule? Incorporating even relatively short bouts of exercise into a daily commute appears to deliver significant rewards, according to a new study from the University of North Carolina at Chapel Hill.

Obama, Pope Focus On Abortion, \'Life\' Issues In First Meeting

In their first meeting, President Obama and Pope Benedict XVI on Friday discussed their views on abortion, embryonic stem cell research and the rights of health care workers to object to procedures and services that go against their beliefs, the Los Angeles Times reports. During a 30-minute discussion, the pope expressed to Obama his beliefs about "the defense and promotion of life and the right to abide by one"s conscience," according to the Vatican. The Times reports that the statement was a "clear reference" to debates over abortion rights, embryonic stem cell research and "conscience" protections for health care providers who refuse care on moral or religious grounds (Chu, Los Angeles Times, 7/11).According to Time, Benedict showed "no intention of papering over differences on what the Vatican calls "life" issues," including abortion rights. Vatican spokesperson the Rev. Federico Lombardi said that the pope told him how Obama "explicitly expressed his commitment to reducing the number of abortions and to listen to the Church"s concerns on moral issues" (Israely, Time, 7/10). According to White House deputy national security aide Denis McDonough, Obama was "eager to find common ground on these issues and to work aggressively to do that" (Simpson/Feller, AP/Boston Globe, 7/11). However, "[I]t may just be that there"s issues that you can"t come to agreement on," McDonough added, noting that Obama believes that "you can disagree without being disagreeable" (Los Angeles Times, 7/11).Montsignor Georg Ganswein, the pope"s personal secretary, said that Obama was given a copy of "Dignitas Personae," or "The Dignity of a Person," a Vatican document released in December detailing the Roman Catholic Church"s most recent stance on bioethics issues (Time, 7/10). The document "hardened" the Church"s opposition to embryonic stem cell research, cloning and in vitro fertilization (AP/Boston Globe, 7/11). Obama assured the pope he would read the document that day on his flight from Italy to Ghana. Ganswein said that the document "can help the president better understand the position of the Catholic Church." Lombardi noted that it "would be ambiguous to hide or minimize what we believe," adding, "It"s not meant to be divisive or polemical" (Time, 7/10).

Obama\'s Focus On Health Care Crucial To Reform

"After a week of international diplomacy, President Obama returns to Washington this week facing an even greater diplomatic challenge: nudging the large and controversial health-care reform package toward consensus on Capitol Hill," The Washington Post reports. Despite media reports of challenges including "the virtual wall of opposition among Republicans," "resistance among conservative Blue Dog Democrats over the potential cost," and "nervousness among progressives that the White House might compromise too much on a public insurance option," officials at the White House "remain publicly optimistic." White House Chief of Staff Rahm Emanuel said that the issues are just part of "the nature of what we"re doing," and that "we"ve never, on universal coverage, been this close to the goal line."

Fly Study Suggests Fasting May Not Be Key To Longer Life

Many studies on flies, mice, and more recently monkeys, have suggested that the key to a longer life is to restrict calorie intake, but a new study

Slumping Economy Hurts Health System, But Stimulus Provides Some Relief

The receding economy has dragged down Michigan"s health care system, "offering a preview of how a lingering recession could corrode Americans" hospitals, savings and health," the Wall Street Journal reports.

Officials Hope Health Reform Reaches Rural America

Rural Americans are hopeful that health reform includes funding for clinics and health care services in their communities, where the cost of care is often high, CNN reports.

New Alliance For Discovery Of WNT Pathway Inhibitors To Be Used In Cancer Therapy

Cancer Research Technology (CRT), Merck Serono, a division of Merck KGaA, Darmstadt, Germany, Cancer Research UK, Cardiff University and The Institute of Cancer Research (ICR) are set to begin a major new research collaboration for the first time. This will provide substantial investment in research on the WNT signalling pathway in the hope of finding new drug targets.

Study Looks At HIV, Risk Behaviors Among Male Clients Of Sex Workers In Tijuana, Mexico

"A large percentage" of U.S. and Mexican men who regularly engage in sexual activity with sex workers in Tijuana, Mexico, do not use condoms and have a history of substance and alcohol use, according to a study published in the online journal AIDS, the Los Angeles Times" blog "L.A. Now" reports. The study, by researchers from Mexico and the University of California-San Diego, surveyed 400 men - both Mexico and U.S. residents - and found that half of the men had unprotected sex with a female sex worker within the last four months. Researchers noted that although Tijuana authorities require that sex workers be registered and tested regularly for HIV, "only about half of [sex workers] have registered or been tested," according to the blog. Thomas Patterson of the UC-San Diego"s department of psychiatry and the Veterans Affairs health center, said the findings indicate a need for an educational campaign targeting men who frequent sex workers (Perry, 7/11).

Study Estimates Radiation Dose, Cancer Risk From Coronary Artery Calcium Screening

A study based on computer modeling of radiation risk suggests that widespread screening for the buildup of calcium in the arteries using computed tomography scans would lead to an estimated 42 additional radiation-induced cancer cases per 100,000 men and 62 cases per 100,000 women, according to a report in the July 13 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

Certain Type Of Implanted Lenses May Be A Treatment Option For Some Patients With Nearsightedness

Implantable lenses made of a collagen-like substance appear to provide stable correction of moderate to high nearsightedness (myopia) over four years of follow-up, according to a report in the July issue of Archives of Ophthalmology, one of the JAMA/Archives journals.

\'World First\' Shows Heart Can Recover, Says British Heart Foundation

In response to the publication of the story of heart transplant patient Hannah Clark in the Lancet , Professor Peter Weissberg, Medical Director of the British Heart Foundation (BHF), described the operation as "an exciting and important event".

Safety And Cognitive Stability Are Key Findings In Phase IIA Trial Of New Alzheimer\'s Disease Treatment From Humanetics Corporation

The results of a preliminary clinical trial suggest that a new Alzheimer"s drug from Humanetics Corporation is safe for daily use and that cognitive performance in patients with mild to moderate disease remained stable during the six-week course of the trial. The lack of decline in cognitive performance was an encouraging finding to be further evaluated in a Phase IIB clinical trial.

New Research Points To Gender Relationships Between Parents And Their Children As Vital Factor In Childhood Obesity

The relationships between children and their parent of the same gender in the earliest years of life could be the key to understanding why some young people become obese and others do not, new research conducted by the EarlyBird Diabetes Study has shown.

Alzheimer\'s Prediction And Diagnosis May Be Improved By Brain Imaging And Proteins In Spinal Fluid

Changes in the brain measured with MRI and PET scans, combined with memory tests and detection of risk proteins in body fluids, may lead to earlier and more accurate diagnosis of Alzheimer"s, according to new research reported at the Alzheimer"s Association 2009 International Conference on Alzheimer"s Disease (ICAD 2009) in Vienna.

Aiming For Early Diagnosis For ADHD And Parkinson\'s Disease

Eye movement tests developed by Queen"s University researchers to aid in understanding childhood brain development and healthy aging may also help in the diagnosis of Attention Deficit Hyperactivity Disorder and detecting the early onset of Parkinson"s disease. The project has received close to $1 million in recent funding from the Canadian Institutes of Health Research (CIHR).

AXURA(R)/AKATINOL(R) Enhances Communication Abilities In Patients With Alzheimer÷´s Disease - for A Longer Integration In Social And Family Life

Memantine improves functional communication skills in patients with moderate to severe Alzheimer"s disease (AD), noticeable by caregivers. These are the study results discussed at the International Conference on Alzheimer"s Disease (ICAD). The data of two recent clinical trials support that AXURA®/AKATINOL® - an uncompetitive NMDA receptor antagonist - effects language skills in AD patients and improves cognitive abilities and functional communication. Leading neurologists emphasize that improvement of communication skills is a meaningful treatment target. Communication breakdown can trigger feelings of frustration in Alzheimer"s patients and these feelings may manifest as behavioral instability. This in turn is known to be a major of caregiver"s burden and distress.

Internists And Other Physician Groups Support Comparative Effectiveness Provisions In Proposed Legislation

The American College of Physicians (ACP) joined with two other physician groups to offer strong support for the Comparative Effectiveness Research (CER) provisions included in the Tri-Committee health reform bill about to be considered in the House. The Tri-Committee, which unveiled its proposed legislation on June 19, is made up of the House Ways and Means, Energy and Commerce, and Education and Labor Committees.

Convicting HIV-Positive People Contributes To Spread Of Virus, Opinion Piece Says

The recent conviction of HIV-positive Toronto resident Johnson Aziga is "part of an upward trend," as more "charges and prosecutions for HIV transmission -- and even potential HIV exposure -- are popping up around the planet," Regan Hofmann, editor-in-chief of POZ, writes in a Dallas Morning News opinion piece. According to Hofmann, the Canadian court that convicted Aziga took "the criminalization of people with HIV to a new level of severity," convicting him of two counts of first-degree murder and 10 counts of aggravated assault. "He"s the first person in the world who was aware of his HIV status to be convicted of first-degree murder for exposing a sexual partner to HIV," she notes. "In some cases, HIV-positive people are being imprisoned even if HIV transmission couldn"t have possibly occurred," she writes, citing a case in Dallas, Texas, last year in which "an HIV-positive man was sentenced to 35 years for harassing a public servant with a "deadly weapon" when he spat on a police officer." Hofmann writes that her decision to be with the partner from whom she contracted HIV involved a risk that exists for "anyone anytime they have intercourse without a condom," adding that while she was "certainly upset at the man who gave me HIV," she is "equally upset with myself for choosing to risk my own life when, arguably, I knew better." She continues, "The finger of justice seems to inevitably wag at the person living with HIV, but given that these cases in question involved consensual sex, it makes me wonder why we are not discussing the culpability of both parties," adding, "Why are we not asking the person who was exposed, and who perhaps contracted HIV, whether they felt any responsibility for the risk they took when having unprotected sex?" According to Hofmann, "Criminalizing people with HIV ... helps deepen the stigma around the disease, which in turn, undermines prevention, testing and treatment efforts," making people less likely to seek out information on HIV, discuss HIV with their partners or get tested. "According to U.S. law, if you don"t know you have HIV, you are less culpable should you pass it along to a partner," Hofmann writes, adding, "This provides a disincentive for people to know their HIV status. And, if people are unaware of their HIV status, they are not seeking care for the disease." Hofmann writes, "When people are aware that they have HIV and seek treatment, their viral load can be reduced, rendering them less infectious." She adds, "Therefore, criminalization of HIV actually leads to the spread of HIV" and deters people from talking about the virus. She concludes, "People should fear" HIV "rather than those whose bodies harbor it. The barrier of stigma wedged between a person and others they deem "dirty" or "derelict" will not keep AIDS at bay" (Hofmann, Dallas Morning News, 5/15).

Ten-Patient Feasibility Study Shows Safety And Potential For Non-Invasive Deep Brain Ablation

InSightec Ltd. announced that a team at the University Children"s Hospital Zurich has completed a feasibility study testing the use of non-invasive transcranial MR-guided focused ultrasound surgery (MRgFUS) for the treatment of neuropathic pain. Ten adult patients diagnosed with chronic neuropathic pain successfully underwent non-invasive deep brain ablation surgery (central lateral thalamotomy) with transcranial MRgFUS and showed improvement in pain scores and reduction of pain medication with no adverse effects at three months follow-up. This is the first study in the world to test non-invasive transcranial focused ultrasound as a treatment modality for functional brain disorders.

Keryx Biopharmaceuticals, Inc. Commences Phase 1 Study Of KRX-0401 (Perifosine) In Recurrent Pediatric Solid Tumors At Memorial Sloan-Kettering Cancer

Keryx Biopharmaceuticals, Inc. (Nasdaq: KERX) announced today the initiation of a Phase 1 clinical study to evaluate KRX-0401 (perifosine) as a single agent treatment for recurrent solid tumors in pediatric patients. This Phase 1 study is now open for enrollment at Memorial Sloan-Kettering Cancer Center in New York City. Oren Becher, MD, Instructor, Department of Pediatrics, in coordination with Eric Holland, MD, PhD, Director of the Brain Tumor group at Memorial Sloan-Kettering Cancer Center, will act as the study"s Principal Investigator. The study announced is being fully funded by an external grant provided by a private organization.

Value Of Pharmacists Will Be On Display At Annual NCSL Summit

The Alliance for Pharmaceutical Care will offer health screenings and present information on vital healthcare issues at "Pharmacist Central", the Alliance"s exhibition at the National Conference of State Legislatures (NCSL) 2009 Legislative Summit, July 20-24 in Philadelphia, Pennsylvania.

Abortion Issue Could Derail Health Reform

Nineteen Democrats have written House Speaker Nancy Pelosi promising not to vote for a health bill that includes funding for abortion, igniting a debate that has the potential to derail a health care overhaul, NPR reports.

Obesity In Pregnancy Increases Risk Of Asthma In Offspring

Babies born to obese mothers may have an increased risk of asthma, according to data from a new study to be presented on May 19 at the 105th International Conference of the American Thoracic Society in San Diego.

NICE Welcomes Office For Life Sciences New Blueprint To Support Innovative Drugs

NICE today welcomed the Office for Life Sciences new Blueprint to support the life sciences industry, which will also improve patient access to innovative new drugs.

Niall Dickson To Join The GMC As New Chief Executive

The GMC has appointed Niall Dickson as the new Chief Executive of the General Medical Council. He will take up his post in January next year.

Scientists Report First Remote, Underwater Detection Of Harmful Algae, Toxins

Scientists at NOAA"s National Centers for Coastal Ocean Science and the Monterey Bay Aquarium Research Institute (MBARI) have successfully conducted the first remote detection of a harmful algal species and its toxin below the ocean"s surface. The achievement was recently reported in the June issue of Oceanography.

Luminex Receives FDA Clearance For An Update To The XTAG(R) Respiratory Viral Panel Package Insert

Luminex Corporation (NASDAQ: LMNX), the worldwide leader in multiplexed solutions, today announced that the U.S. Food and Drug Administration (FDA) has cleared labeling updates for the company"s xTAG® Respiratory Viral Panel (RVP) to include data about the performance of the test in humans infected with the pandemic strain of influenza A, 2009 influenza A/H1N1, which is sometimes referred to as "swine flu." The test"s labeling has been updated to include information from two new studies that demonstrate that xTAG RVP can be an effective aid in the detection of 2009 Influenza A/HIN1, but cannot identify the hemagglutinin gene of the 2009 Influenza A/H1N1 in clinical specimens.

New Technique Could Sustain Cancer Patients\' Fertility

Researchers funded by the National Institutes of Health have completed a critical first step in the eventual development of a technique to retain fertility in women with cancer who require treatments that might otherwise make them unable to have children.

Potential For Delivering Antibiotic Treatment Via Aerosol

Aerosol delivery of antibiotics via nanoparticles may provide a means to improve drug delivery and increase patient compliance, thus reducing the severity of individual illnesses, the spread of epidemics, and possibly even retarding antibiotic resistance.

Experts At Leading Vision Health Care Organization Offer 5 Summer Eye Safety Tips

As summer vacations begin, experts at Lighthouse International urge everyone to take eye safety seriously and prevent damage from the sun that could be permanent. Lighthouse International, based in New York City, is the 104 year old non-profit leader in vision health.

Kaiser Permanente Survey Shows Seniors Embrace Internet To Manage Their Health

New data show that Medicare beneficiaries registered to use My Health Manager, Kaiser Permanente"s personal health record, are overwhelmingly satisfied with using the Internet to manage their health care online. Results from the recent Kaiser Permanente survey examining Web site usage and Medicare beneficiary satisfaction were presented today at the World Health Care Congress" 5th Annual Leadership Summit on Medicare in Washington, D.C.

Noven Reports Positive Phase 2 Results For Mesafem™ Non-Hormonal Therapy For Vasomotor Symptoms

Noven Pharmaceuticals, Inc. (NASDAQ:NOVN) announced positive top-line results from its Phase 2 clinical study evaluating Mesafem™ (low-dose paroxetine mesylate) for the treatment of vasomotor symptoms (hot flashes) associated with menopause ("VMS").

Roche NimbleGen CGH Arrays Enable Characterization Of Novel Genomic Disorders Associated With Psychiatric Disease In Recent Studies

High-resolution comparative genomic hybridization (CGH) has rapidly emerged as the method of choice for molecular cytogenetic detection and characterization of chromosomal abnormalities associated with mental retardation, cancer, and other complex phenotypes. In two recent studies published in the Journal of Medical Genetics (1, 2), high-resolution NimbleGen CGH arrays were used to further characterize two recently identified genomic disorders (3, 4).

A Phase III Alzheimer\'s Drug Increases Levels Of Beta Amyloid In The Brain -- But Still Provides Benefits

Surprising new insights into how a Phase III Alzheimer"s drug might work

Comment On Dimebolin (dimebon) Increasing Brain Beta Amyloid In Mouse Models

Dimebolin, originally administered as an antihistamine, has previously been found to help slow the decline of cognitive ability in participants.

Expert Statement Issued About Lantus(R) Following Recent Publications In Diabetologia

Sanofi-aventis (EURONEXT: SAN and NYSE: SNY) announced the release of an Expert Statement by a multidisciplinary board of renowned international experts following an in-depth assessment of the recent publications of registry analyses with Lantus(R) (insulin glargine [rDNA] injection) in Diabetologia. This board of international specialists in the field of endocrinology, oncology and epidemiology came to the conclusion, that all four manuscripts have significant methodological limitations and shortcomings, and that they provide inconsistent and inconclusive results regarding a potential link between insulin glargine use and an increased risk of cancer.

Study To Assess Hip Exercises As Treatment For Osteoarthritis In The Knee Joints

Researchers at Rush University Medical Center are testing a novel regimen of hip-muscle exercises to decrease the load on the knee joints in patients with osteoarthritis. The goal is not only to relieve pain but also, possibly, to halt progression of the disease.

Can Children Outgrow Chronic Daily Headache?

Most children who suffer from chronic daily headache may outgrow the disabling condition, according to research published in the July 15, 2009, online issue of Neurology®, the medical journal of the American Academy of Neurology. Nearly 1.5 percent of middle school children are affected by chronic daily headache, which includes chronic migraines and tension-type headaches.

New Map Of Genomic Variation WIll Enable Disease Research

Genetics researchers have unveiled a powerful new re for scientists and health providers studying human illnesses--a reference standard of deletions and duplications of DNA found in the human genome. Drawn from over 2,000 healthy persons, the study provides one of the deepest and broadest sets of copy number variations (CNVs) available to date, along with a new research tool for diagnosing and identifying genetic problems in patients.

What Is Allergic Conjunctivitis? What Causes Allergic Conjunctivitis?

Most people get allergic conjunctivitis when their eyes come into contact with an allergen - a substance which makes the body"s immune system overreact. The eye becomes sore, inflamed and sometimes painful. Symptoms occur because the overreacting immune system makes the body release histamine and other active substances by mast cells - these cause dilation of blood vessels (blood vessels expand, widen), which irritates the nerve endings and causes increased secretion of tears.

New Path For Cocaine Addiction Research

Cocaine is one of the oldest drugs known to humans, and its abuse has become widespread since the end of the 19th century. At the same time, we know rather little about its effects on the human brain or the mechanisms that lead to cocaine addiction. The latest article by Dr. Marco Leyton, of the Montreal Neurological Institute (MNI), McGill University and the McGill University Health Centre, which was published in the journal Biological Psychiatry on May 15, 2009, not only demonstrates a link between cocaine and the reward circuits in the brain but also associates the susceptibility to addiction with these mechanisms.

RCN Statement On Lord Ara Darzi

Commenting on news that Lord Ara Darzi will stand down as a government minister, Dr Peter Carter, Chief Executive of the Royal College of Nursing (RCN), paid tribute to his contribution to the health service. He said:

NICE Issues Positive Final Appraisal Determination Recommending The Use Of Basilea\'s Toctino

Basilea Pharmaceutica Ltd. (SWISS: BSLN) announces that the National Institute for Health and Clinical Excellence (NICE) issued the Final Appraisal Determination (FAD) recommending the use of Toctino® (alitretinoin) within its licensed indication, as a treatment option for adults with severe chronic hand eczema that has not responded to potent topical corticosteroids.

Regulator Says NHS Must Do More To Protect Children From Neglect And Abuse

CQC publishes national review of NHS child safeguarding

Despite Some Progress, Key Senators Say August Deadline A Longshot

One day after President Obama told lawmakers to speed up their pace, three key Finance Committee senators expressed doubts about meeting the President"s August deadline for passing a reform proposal, Politico reports. Sen. Kent Conrad, D-N.D., said he doesn"t "see how" his colleagues can confirm the new Supreme Court nominee, Sonia Sotomayor, and pass a health bill in the time left before the August recess.

Life Sciences Sector Applauds Office For Life Sciences "Life Sciences Blueprint" As A Major Milestone Towards Securing The Future Of The UK Industry

The UK"s life sciences trade associations - the Association of British Healthcare Industries (ABHI), the Association of the British Pharmaceutical Industry (ABPI), the BioIndustry Association (BIA) and the British In Vitro Diagnostic Association (BIVDA) - believe the package of measures announced today by the Office for Life Sciences in its "Life Sciences Blueprint" provide an excellent basis for firmly securing the future of the life sciences sector and re-establishing the UK"s global competitive position.

J & J: Hospital Deal Will Hurt Medical Device Sales

The CFO for Johnson & Johnson"s said President Obama"s deal with hospitals to cut Medicare costs will reduce the sales of medical devices, Bloomberg reports: "Hospitals buy medical devices, including J&J"s artificial hips and stents to prop open clogged arteries, directly from the manufacturer, (Johnson and Johnson CFO Dominic) Caruso said today in an interview with Bloomberg News. The hospitals are reimbursed by government-run health plans for the cost of a procedure regardless of the price of the equipment, pressuring hospitals to cut purchases of the latest technologies, he said. ò€¦ "The deal that the hospital industry struck will obviously have an impact on the medical-device business," Caruso said. "Medicare reimburses the hospital for a basket of costs related to a procedure, of which medical devices are included"" (Randall, 7/14).

Realistic Perception Of Risk Is Key To Motivate People To Take Protective Action Against New Infectious Diseases

With the current outbreak of swine flu, and in the absence of a vaccine or treatment at present, the only way to contain the virus is to get people around the world to take precautionary measures. In a special editorial1 in the latest issue of Springer"s International Journal of Behavioral Medicine, Johannes Brug, Arja Aro, and Jan Hendrik Richardus show that there are three key parameters that convince people to take precautions. Firstly, they need to be aware of the risk to them. Secondly, they need to believe that effective protective actions are available and have confidence in them. Lastly, communications about risk need to be carefully managed so that they express the actual risk accurately to prevent mass scares.

New Report: Private And Public Insurance Choices Would Help Reduce Administrative Health Care Costs By $265 Billion Over 10 Years

As lawmakers debate how to pay for an overhaul of the nation"s health care system, a new report from The Commonwealth Fund projects that including both private and public insurance choices in a new insurance exchange would save the United States as much as $265 billion in administrative costs from 2010 to 2020. Congressional leaders are attempting to keep 10-year federal budget costs of health care reform legislation under $1 trillion.

Processing In The Brain\'s Reward Pathways May Be Affected By Childhood Adversity

New research shows that childhood adversity is associated with diminished neural activity in brain regions implicated in the anticipation of possible rewards.

Vehicle Designed For Blind To Take The Wheel

A student team in the Virginia Tech College of Engineering is providing the blind with an opportunity many never thought possible: The opportunity to drive.

New Mechanism Controlling Neuronal Migration Discovered By St. Jude Scientists

The molecular machinery that helps brain cells migrate to their correct place in the developing brain has been identified by scientists at St. Jude Children"s Research Hospital. The finding offers new insight into the forces that drive brain organization in developing fetuses and children during their first years. Disruption of this brain-patterning machinery can cause epilepsy and mental retardation and understanding its function could give new insight into such disorders.

Link Between Social Reasoning And Brain Development In Preschoolers -- Queen\'s Study

New research at Queen"s University shows that the way preschool children understand false beliefs can be linked to particular aspects of brain development. This landmark research may aid in understanding developmental disorders such as autism.

OneTouch(R) Ping™ Glucose Management System Approved By Health Canada

Animas Corporation announcedthe approval of its OneTouch® Ping™ Glucose Management System by Health Canada. OneTouch Ping is the first full-feature insulin pump that wirelessly communicates with a blood glucose meter-remote. Using the OneTouch Ping meter-remote, a person can calculate insulin doses and opt to wirelessly instruct the pump to deliver them without touching the pump at all, giving patients more freedom and flexibility in using their insulin pump.

Quality Data Made Accessible To Clinical Teams

NHS clinical teams will have access to data showing their performance against a set of more than 200 indicators of high quality care in the NHS in one place. It is the next phase in the drive to help NHS professionals improve the quality of care they deliver to patients, and will also support providers and commissioners of NHS services.

Important Questions Raised About Genetic Research Based Only On Blood Samples; New Treatment In Vascular Disease Foreseen At The Same Time

Research by a group of Montreal scientists calls into question one of the most basic assumptions of human genetics: that when it comes to DNA, every cell in the body is essentially identical to every other cell. Their results appear in the July issue of the journal Human Mutation.

Health Protection 2009 Conference - Programme Announced, UK

The Health Protection Agency (HPA) has announced an innovative and wide-ranging programme for the Health Protection 2009 conference, which is taking place at Warwick University from 14th to 16th September.

ADVTX Announces New Treatment For Bleeding After Nuclear Exposure

Advanced Therapeutics & Co. (ADVTX) announced that Fibrinoplate-S™ has shown efficacy in reducing the bleeding in animals exposed to extreme doses of radiation. Survivors of a nuclear event or a dirty bomb explosion will have similar damage from the ionizing radiation of such bombs.

Institute For OneWorld Health And Novartis Launch Innovative Collaboration To Discover And Develop Novel Therapy To Combat Diarrheal Disease

The Institute for OneWorld Health, the US-based non-profit pharmaceutical company that develops drugs for people with neglected infectious diseases in the developing world, today announced that it has launched a collaboration with global pharmaceutical leader Novartis to discover and develop a novel therapy for secretory diarrhea, a deadly disease that kills more than 1.6 million children in the developing world each year.

Does Your Child Need Vision Therapy?

The College of Optometrists in Vision Development (COVD) launched their annual campaign to educate the public on the steps they can take to ensure their children aren"t struggling with reading and learning because of undiagnosed vision problems.

Baking Soda: For Cooking, Cleaning, And Kidney Health?

A daily dose of sodium bicarbonate baking soda, already used for baking, cleaning, acid indigestion, sunburn, and more slows the decline of kidney function in some patients with advanced chronic kidney disease (CKD), reports an upcoming study in the Journal of the American Society of Nephrology (JASN). "This cheap and simple strategy also improves patients" nutritional status, and has the potential of translating into significant economic, quality of life, and clinical outcome benefits," comments Magdi Yaqoob, MD (Royal London Hospital).

Poll Reveals Americans Wary About U.S. Healthcare Reform

Americans are unsure that a healthcare reform bill introduced this week is the solution to problems with the U.S. healthcare system, according to a poll created and commissioned by a public policy expert at The University of Texas Health Science Center at Houston.

Higher Speed Limits Cost Lives

The repeal of the federal speed control law in 1995 has resulted in an increase in road fatalities and injuries, according to researchers at the University of Illinois at Chicago School of Public Health.

Nurses Call On Rep. Miller To Support Amendment Allowing States To Enact Single-Payer Health Reform

With debate underway in the House Education and Labor Committee today on the sweeping healthcare reform bill in that body, the nation"s largest organization of registered nurses today called on Committee Chair George Miller to support a critical amendment that would enable individual states to go a step farther and adopt single-payer, Medicare-for-All style reforms.

Obama Presses Lawmakers On Health Reform

In President Obama"s push for health reform, "new fault lines are opening up everywhere you look. Liberals are worried that Obama is going squishy on including a strong, government-run "public option" among the health-care choices available to Americans. Conservatives are warning that the legislation won"t do enough to control health costs. Rural lawmakers are complaining that proposed Medicare cuts will fall too hard on their states," TIME reports. "And those are just the arguments going on among the Democrats. It"s all a sign that the season for hard decisions has arrived. Obama continues to project an air of confidence about the most audacious undertaking of his presidency" (Tumulty, 7/16).

Senate Panel Advances Health-Care Overhaul, But Battle Lines Sharpen

"President Obama"s ambitious drive to overhaul the nation"s $2.3 trillion health-care system cleared a key Senate committee yesterday. But the administration was promptly buffeted by criticism from some of the industry players and moderate Democrats it has courted for months, calling into question the prospects for a bipartisan landmark bill," The Washington Post reports. This is the "the first time in 15 years a congressional panel has endorsed coverage for all. ò€¦ But the 13 to 10 party-line vote, after rancorous comments by the top Republican on the committee, underscored the mounting tensions in Congress and the country over the president"s signature item. From one end of Pennsylvania Avenue to the other, lawmakers, lobbyists and the president himself all moved quickly to position themselves for the intensifying battle."

FDA Reviewing Preliminary Safety Information On Asthma Drug Xolair

The U.S. Food and Drug Administration announced that it is conducting a safety review of Xolair (omalizumab), a drug used to treat certain adults and adolescents with moderate-to-severe persistent asthma.

Cost Emerges As Lightning Rod Issue

The cost of health care reform has emerged as a key battle in overhaul efforts. Attention is being paid to how costs will affect specific groups including the middle class and businesses.

Obama Administration Proposes Big Changes In Medicare Payment Oversight

Determined to cut Medicare costs, the White House unveiled a plan that would shift much of the power over Medicare payment rates from Congress to the executive branch.

Hospital Rankings Released By U.S. News And World Report

"This is Year 20 for America"s Best Hospitals, a tool for patients who need medical sophistication that most facilities are unable to provide," reports U.S. News and World Report. The magazine ranked hospitals based on how well they did in "complex and demanding situations" such as "replacing an 85-year-old"s heart valve, diagnosing and treating a spinal tumor, and dealing with inflammatory bowel disease." Out of a total 4,861 hospitals analyzed, "Only 174 hospitals scored high enough to be ranked in even one of the 16 specialties. And of these, just 21 qualified for [the] Honor Roll by ranking at or near the top in at least six specialties." The ranking list includes the 50 highest scoring hospitals (Comarow, 7/15).

South American Health Ministers Gather In Argentina To Discuss H1N1 Preparedness

The health ministers of six South American countries gathered in Buenos Aires, Argentina, on Wednesday to "coordinate defenses against" the H1N1 (swine flu) virus which has killed nearly 200 people in the region," the AFP/Google.com reports. Ministers from Argentina, Bolivia, Brazil, Chile, Paraguay and Uruguay used the meeting to voice concern over the rapid spread of the H1N1 virus in their countries, which are now in the southern hemisphere"s winter months, and discuss ways to share supplies to help prevent the spread of the virus. The article includes the individual strategies being taken by some South American countries (7/15).

Our Metallic Reflection: Considering Future Human-Android Interactions

Everyday human interaction is not what you would call perfect, so what if there was a third party added to the mix - like a metallic version of us? In a new article in Perspectives on Psychological Science, psychologist Neal J. Roese and computer scientist Eyal Amir from the University of Illinois at Urbana-Champaign investigate what human-android interactions may be like 50 years into the future.

Thalidomide Does Not Improve Survival In Small Cell Lung Cancer: Journal Of The National Cancer Institute News Brief

Treating patients with thalidomide in combination with chemotherapy for small cell lung cancer (SCLC) did not improve their survival but did increase their risk of blood clots, according to a new study published online July 16 in the Journal of the National Cancer Institute.

Patient Satisfaction At Discharge From Hospital Improved By Hospital Software

When hospitalists use discharge communication software, patients and the outpatient doctors who carry out the care have better perceptions of the quality of the discharge process, according to new research published in the August issue of the Journal of Hospital Medicine.

New Ways To Extend Professional Regulation

New alternatives to statutory regulation for currently unregulated health and occupational professions have been proposed by a specialist working group, Health Minister Ann Keen announced recently.

Out Of Control: Spiralling Number Of Deadly Hepatitis C Infections As Government Strategy Fails. Urgent Call To Action To Halt Imminent Liver Crisis

New research demonstrates that a large majority (70%) of Strategic Health Authorities (SHAs) in England are failing to oversee the Government"s strategy to tackle hepatitis C1, leaving infection rates of this deadly virus to increase and causing the disease to spiral out of control - putting thousands of lives at risk. A further study shows SHAs ignoring NICE guidance with only 29% of diagnosed patients2 being treated across the country, less than half of the 60% that NICE recommends.3

Secrets Of A Life-Giving Amino Acid Revealed By Yale Researchers

Selenium is a trace element crucial to life - too little or too much of it is fatal. In the July 17 issue of the journal Science, researchers at Yale University and University of Illinois at Chicago detail the molecular mechanisms that govern its metabolism in the human body.

BioCryst Pharmaceuticals Reports Positive Results Of Shionogi & Co. Sponsored Phase 3 Studies Of I.v. Peramivir For Influenza

BioCryst Pharmaceuticals (Nasdaq: BCRX) announced positive results from two Phase 3 studies of intravenous (i.v.) peramivir in patients with seasonal influenza. The studies were sponsored by BioCryst"s partner Shionogi & Co., Ltd. of Osaka, Japan and conducted during the 2008-2009 influenza season. Shionogi and Green Cross Corporation, the license holder of peramivir in Korea, co-conducted the portion of the studies in Korea.

Home Oxygen Patients And Family Members Visit Capitol Hill To Ask Congress To Protect Medicare Home Oxygen Therapy Benefit

Asking members of Congress to support patient-focused reform of the Medicare home oxygen therapy benefit, patients and family members with the National Emphysema/COPD Association (NECA), a national advocacy organization representing patients with chronic obstructive pulmonary disease (COPD) and other lung diseases, descended on Capitol Hill this week. Patients urged members of the U.S. House to support and pass the Medicare Home Oxygen Therapy Act of 2009 (H.R. 3220), which was recently introduced.

CBO: Health Reform Bills Bend Cost Curve In Wrong Direction

"Congress"s chief budget analyst delivered a devastating assessment yesterday of the health-care proposals drafted by congressional Democrats, fueling an insurrection among fiscal conservatives in the House and pushing negotiators in the Senate to redouble efforts to draw up a new plan that more effectively restrains federal spending," the Washington Post reports.

Dying At Home: A Trend That Could Make Hospitals More Efficient

Hospitals across Canada are seeking ways to free up beds. University of Alberta researcher Donna Wilson has a suggestion: people should be encouraged to die at home rather than in hospital.

Mass. Panel Recommends Scrapping Doctors, Hospitals Payment System

The Boston Globe: "A state commission recommended yesterday that Massachusetts dramatically change how doctors and hospitals are paid, essentially putting providers on a budget as a way to control exploding healthcare costs and improve the quality of care. The 10-member commission, which includes key legislators and members of Governor Deval Patrick"s administration, voted unanimously to largely scrap the current system, in which insurers typically pay doctors and hospitals a negotiated fee for each individual procedure or visit. That arrangement is widely seen as leading to unneeded tests and procedures. Instead, the group wants private insurers and the state and federal Medicaid program to pay providers a set payment for each patient that covers all that person"s care for an entire year and to make the radical shift within five years" (Kowalczyk, 7/17).

C. elegans Poster Award Recipients Announced By Genetics Society Of America

The Genetics Society of America is pleased to announce the recipients for the first place poster awards from the 17th International C. elegans meeting held June 24-28 at the University of California, Los Angeles. Eighteen posters from among the 375 graduate posters reviewed by the selection committee were selected for the first award of $55 (US).

NHS South West Essex Launches Mobile MMR Clinic To Tackle Outbreak, UK

NHS South West Essex has launched an ambitious mobile MMR immunisation programme to improve vaccination rates among 20,000 at risk children.

Renowned Surgeon Examines Our Most Significant Contributions To Surgery - From Crude Procedures To Precision Operations

As a result of the scientific advances and medical innovations made in the twentieth century, the United States today occupies an established and unchallenged leading role in the field of surgery. Renowned surgeon Seymour I. Schwartz, MD, gives a sweeping history of American surgical practice in "Gifted Hands: America"s Most Significant Contributions To Surgery" (Prometheus Books). He describes how surgery in the United States has advanced from the comparatively crude practices of pioneering physicians in the pre-Columbian and colonial eras to its current level of preeminence in scientific surgery today.

Asthma Mucus Myth Slammed

As the winter cold and flu season tightens its grip, the National Asthma Council Australia is concerned that Australians may be incorrectly pointing the finger at milk as the mucus-causing culprit.

Doctor Shortage To Worsen As One Third Of GPs Retire Early, Australia

A third of Western Australian GPs aged 45-65 years plan to retire early, potentially deepening Australia"s medical workforce shortage, according to research published in this year"s General Practice edition of the Medical Journal of Australia.

New Delhi: AHF India Cares Launches \'LOVE Condom\' Campaign

AIDS Healthcare Foundation (AHF) is launching its "LOVE Condom" campaign with an event today in the New Delhi region on the 18th of July, 2009. The campaign includes the distribution of free AHF "LOVE"-brand condoms, as well as a "Stay Negative" public service advertising campaign. Bollywood actor Ronit Roy will be the chief guest at today"s launch event. The event will be at Metropolitan Hotel Nikko, New Delhi. This campaign will be a new start of HIV AIDS education in India.

State Psychiatric Technicians Ask Californians To \'Support Our Services\'

The California Association of Psychiatric Technicians will begin informational pickets next Wednesday at state hospitals, developmental centers and prisons, drawing attention to ongoing cuts that are not only hurting employees, but also the vital services Psych Techs provide to Californians in their care.

Johns Hopkins School Of Medicine To Offer New Degree Program In Informatics

A new, intensive, one-year master"s degree program designed to prepare graduates for informatics leadership positions in clinical, public health and scientific settings will be offered beginning in September by the Johns Hopkins University School of Medicine. The Maryland Higher Education Commission (MHEC) approved the new program in June.

Risk Factors For Cardiovascular Disease Increasing In Younger Canadians Raise Concern About Future Rise In Heart Disease

The prevalence of heart disease and certain key risk factors - hypertension, diabetes, and obesity - are increasing in all age groups and most income groups in Canada found a new study published in CMAJ (Canadian Medical Association Journal) http://www.cmaj.ca/press/cmaj081629.pdf. This study, which looked at national data from 1994 to 2005, encompassed people aged 12 years and older sampling from Canadians of all socioeconomic and ethnic groups. Risk factors such as hypertension, diabetes, and obesity increased most rapidly among younger people between 12 to 50 years of age.

H1N1 Influenza Pandemic Modelling For Public Health Action

Mathematical modelling can help inform public health policy in outbreaks such as the H1N1 pandemic, write members of the Pandemic Influenza Outbreak Research Modelling Team in Canada in a CMAJ (Canadian Medical Association Journal) article http://www.cmaj.ca/press/cmaj090885.pdf. These models are useful tools for simulating plausible scenarios, developing control strategies and identifying important areas for immediate research.

International Team Tracks Clues To HIV

Rice University"s Andrew Barron and his group, working with labs in Italy, Germany and Greece, have identified specific molecules that could block the means by which the deadly virus spreads by taking away its ability to bind with other proteins.

Associative Sequence Learning: The Role Of Experience In The Development Of Imitation And The Mirror System

The ability to imitate is crucial for human social interaction and cultural inheritance. Until recently, it was assumed that this ability was innate. We review new evidence indicating that experience plays a critical role in the development of imitation.

Top Obama Administration Officials Hold Rural Health Community Forum

U.S. Department of Health and Human Services Secretary Kathleen Sebelius, U.S. Department of Agriculture Secretary Tom Vilsack, U.S. Department of Labor Secretary Hilda Solis and U.S. Department of Veterans Affairs Secretary Eric Shinseki will host a rural health community forum in St. John Parish, Louisiana, as part of the Obama Administration"s Rural Tour.

David Cameron Makes Autism Pledge And Backs Autism Bill

Commenting on today"s speech by Conservative Party Leader Rt

People Should Pay ÷£20 To See GP Suggests Think Tank

An independent UK think tank has suggested people should pay ÷£20 to see their GP, as a way to relieve the financial squeeze facing the National

FDA Approves NovoLog(R) Labeling Update Increasing The Time Patients Can Use And Store NovoLog(R) In Their Pumps From Two Days To Six Days

Diabetes patients taking NovoLog® (insulin aspart [rDNA origin] injection) can now use the insulin in their pump for up to six days following the U.S. Food and Drug Administration (FDA) approval of a labeling change, diabetes care company Novo Nordisk announced today.[i] The previous label allowed for NovoLog® to be stored in the pump reservoir for two days. This makes NovoLog® the first and only rapid-acting insulin with this extended in-use time.

Perforomist Inhalation Solution Data Presented At American Thoracic Society Conference

Data from two presentations highlighting the use of Perforomist® (formoterol fumarate) Inhalation Solution in moderate to severe chronic obstructive pulmonary disease (COPD) patients were featured at the International Conference of the American Thoracic Society in San Diego. In one analysis, use of Perforomist Inhalation Solution, when added to maintenance tiotropium, resulted in improved pulmonary function, dyspnea (shortness of breath) and rescue medication use versus treatment with tiotropium alone. In a second study, patient satisfaction increased in those treated with Perforomist Inhalation Solution twice daily compared with ipratropium/albuterol metered-dose inhaler (MDI) four times daily.

Swine Flu Pandemic Weekly Report, Wales

Key points

Common Cold Virus Efficiently Delivers Corrected Gene To Cystic Fibrosis Cells

Scientists have worked for 20 years to perfect gene therapy for the treatment of cystic fibrosis, which causes the body to produce dehydrated, thicker-than-normal mucus that clogs the lungs and leads to life threatening infections.

AMSA Avant Research Bursary Winners And Applications For 2010

Congratulations to the winners of the 2009 Avant/AMSA Student Research Fellowship:

THT Launches Mambo Online, A Major New Sexual Health Re For Africans Online

HIV and sexual health charity Terrence Higgins Trust (THT) is pleased to announce the launch of Mambo Online (http://www.mambo.org.uk), a major website dedicated to raising awareness of HIV and sexual health specifically among African communities. The service will go live on 20 July.