Sexual Health
Eli Lilly and Company (NYSE: LLY) announced it will begin enrolling patients this month in two separate but identical Phase III clinical trials of solanezumab(i), previously referred to as LY2062430, an anti-amyloid beta monoclonal antibody being investigated as a potential treatment to delay the progression of mild to moderate Alzheimer"s disease. The trials, called EXPEDITION and EXPEDITION 2, will each include a treatment period that lasts 18 months and are expected to enroll a total of 2,000 patients age 55 and over from 16 countries.
Dialysis takes hours of kidney disease patients" time several days a week, so why not do it at night while sleeping? Overnight dialysis is more convenient for some patients and offers significant benefits over shorter daytime treatments, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN). The findings indicate that overnight dialysis is a viable alternative for patients with irreversible kidney disease, particularly in dialysis clinics where there are constraints on time and res.
Alkermes, Inc. (NASDAQ: ALKS) announced the initiation of two new clinical trials of ALKS 33, an oral opioid modulator for the potential treatment of addiction and other nervous system disorders. Study ALK33-004 is a phase 1 clinical trial designed to examine the ability of ALKS 33 to block the effects of an opioid following a single oral dose of ALKS 33 in healthy, non-dependent, opioid-experienced subjects. Study ALK33-003 is a phase 1 clinical trial designed to evaluate the pharmacokinetics, safety and tolerability of multiple doses of ALKS 33 in healthy volunteers.
A man who used a forged document to obtain an NHS bursary and train as a mental health nurse has been sentenced to 21 months in prison for fraud at Sheffield Crown Court (18 May 2009) after a joint investigation by NHS Counter Fraud and the UK Border Agency.
The 62nd World Health Assembly opened in Geneva, as officials from 193 member countries began their annual review of the activities of the World Health Organization and set new priorities for the future.
The advanced wound management market in Europe is experiencing high growth due to the heightened need for better and more cost-effective treatment. As a result, the market is expanding strongly despite significant hurdles, including intense competition and low reimbursement.
Dynavax Technologies Corporation (Nasdaq:DVAX) announced the award of a Small Business Innovation Research (SBIR) grant by the National Institute of Allergy and Infectious Diseases (NIAID). This grant will support the preclinical development of Dynavax"s first-in-class oligonucleotide-based Toll-like Receptor (TLR) inhibitors for use in inflammatory skin diseases such as psoriasis, cutaneous lupus, and dermatomyositis. This new two-year $700,000 grant is in addition to a $1.8 million grant awarded in 2008.
Although the number of blacks who are registered as organ donors in Michigan has increased in the last 15 years, many are still reluctant to be organ donors, the Detroit News reports. According to Remonia Chapman, director of Gift of Life Michigan"s minority organ tissue transplant education program, many blacks are hesitant to participate with the organ donor registry because they have inadequate access to health care.Chapman said that increased awareness and education about organ donation and the diseases that lead to the need for donated organs, as well as partnerships with minority donors, black ministers and community groups, have encouraged more blacks to be organ donors. In the last 15 years, the percentage of black Michigan residents who are registered organ donors has increased from 10.8% to 21%, with overall minority registration at 24%. Chapman noted that about 41.3% of people on Michigan"s transplant waiting list and about 46% of people in need of a kidney are minorities.According to the News, minority donors are the best matches for minority organ recipients because the genetic profiles of the donor and recipient will have more similarities. Chapman added that the best matches for kidney recipients are donors from the recipient"s family or from the recipient"s ethnic group if a family donor is not available (Stolarz, Detroit News, 5/19).
Zannos Grekos, MD, a featured speaker at the at the 17th Annual World Congress on Anti-Aging Medicine and Regenerative Biotechnologies, announced one year follow-up results for a pulmonary hypertension patient treated with his own activated stem cells.
BioAlliance Pharma SA (Paris:BIO), a company dedicated to therapies and supportive care for cancer and AIDS patients, announced its scientific communications at upcoming international conferences on infectious diseases and oncology:
Climate change is this century"s biggest threat to human health according to a major report by an interdisciplinary team of academics
Four-year results of a large, multi-center clinical trial show that earlier results favoring the CYPHER® Sirolimus-eluting Coronary Stent over bare metal stents (BMS) in patients with acute myocardial infarction (heart attack) were maintained in long-term follow-up. In addition, there were no differences in key safety measures between the CYPHER® Stent and BMS.
Research led by David Worthylake, PhD, Assistant Professor of Biochemistry and Molecular Biology at LSU Health Sciences Center New Orleans, may help lay the groundwork for the development of a compound to prevent the spread of cancer. The research will be published in the May 29, 2009 issue of the Journal of Biological Chemistry.
Inuit children have the highest rate of hospital admission for Lower respiratory tract infections (LRTIs) globally, but new research shows that lowering risk factors though public health interventions and an enhanced immunization program could improve health for Inuit children and lower health care costs significantly. The first-of-its-kind case control research was conducted by Dr. Anna Banerji, a pediatric infectious disease specialist and researcher at St. Michael"s Hospital.
A new species of yeast has been discovered deep in the Amazon jungle. In a paper published on-line in FEMS Yeast Research, IFR scientists and colleagues from Pontificia Universidad CatÃölica del Ecuador describe the novel characteristics of Candida carvajalis sp. nov.
This is a personal account of my battle so far with prostate cancer. My name is Christian Nordqvist, 53, Editor of Medical News Today. On 26th of March, 2009, I underwent a radical prostatectomy - in other words, I had my prostate taken out. A biopsy had detected cancerous tissue in the prostate. Before that, a routine check-up had revealed higher than normal levels of PSA in my blood. After discussing various options with my urologist, we decided that radical prostatectomy was best for me. There were two compelling reasons for this - I am 53 (relatively young for this type of disease), and I have a family history of prostate cancer.
Scientists have determined how to produce replication-competent viruses
A class of drugs already approved as cancer treatments might also help to beat alcohol addiction. That"s the conclusion of a discovery in flies of a gene, dubbed happyhour, that has an important and previously unknown role in controlling the insects" response to alcohol.
Women who develop gestational diabetes (GD) during pregnancy have a seven-and-a-half times increased risk of developing type 2 diabetes post-birth, which lasts throughout their lifetime. However, there is no agreed policy on the long-term follow up of these women and many do not return for the currently recommended 6-week post-birth diabetes check. An Article in this week"s diabetes special issue of The Lancet says that the strength of the association suggests that both disorders have an overlapping cause-and this should act as an incentive for women to attend the recommended post-birth check. This attendance could be an opportunity to provide advice on diet and exercise, and treatments to delay or prevent onset of diabetes-as well as alerting these women to symptoms of future diabetes, and to alert general practitioners responsible for their long-term care.
Lyrica is Pfizer"s trade name for a drug called pregabalin. Pregabalin is an anticonvulsant (anti-seizure) drug that is often used to treat neuropathic pain as well as partial seizures that are common in temporal lobe epilepsy. In Europe, pregabalin is also approved to treat generalized anxiety disorder.
First results from a large tissue survey in Britain of the agent that causes variant Creutzfeldt-Jakob disease (vCJD) are unable so far to establish that the prevalence is lower than that given by previous estimates, concludes a study published on bmj.com today.
Genomic Health, Inc. (Nasdaq: GHDX) announced positive results from the landmark QUASAR validation study, which demonstrated that the Oncotype DX(R) colon cancer test can independently predict individual recurrence risk in stage II colon cancer patients following surgery. Importantly, the Oncotype DX colon cancer Recurrence Score(R) provided additional independent clinical value beyond standard measures. The study showed that the colon cancer Recurrence Score maintained significance (p=0.008), independent of mismatch repair (MMR), also known as MSI (Microsatellite Instability), T-stage, nodes examined, grade and lymphovascular invasion.
Geneticists at Signature Genomic Laboratories recently demonstrated that microarray-based genetic testing can identify chromosome abnormalities that cause genetic disorders associated with susceptibility to cancer prior to the onset of symptoms.
In celebration of scientific and business partnerships that have extended the lives of thousands of myeloma patients, the Eighth Annual Multiple Myeloma Research Foundation (MMRF) held its Chicago Awards Dinner on May 19th at the Four Seasons Hotel in Chicago. Legendary football coach and ESPN analyst, Lou Holtz, was joined by Mistress of Ceremonies Bonnie Hunt and keynote speaker Dr. Mark Chelsky to celebrate with over 500 Chicago corporate business leaders in the quest for a cure for the deadly blood cancer.
According to the Health Protection Agency (HPA), UK, there were five new confirmed cases of swine flu (H1N1), bringing the total to 117. The HPA"s laboratories carry out all testing of swine flu virus. The five new cases include two adults from London, two adults from South East England, and a child from the West Midlands. Two of them returned from a country where swine flu exists, while another is linked to a previously confirmed case in England - the s of the other two are still being investigated, the HPA reported. Nobody in the UK has died from swine flu.
Implementing proposed reductions in the number of hours medical residents work could cost as much as $2.5 billion annually, according to a recent study published in the New England Journal of Medicine, the Baltimore Sun reports. The study follows an Institute of Medicine report that proposed reducing the maximum hours that residents can work without sleep from 30 to 16, increasing the number of days they must take off and improving their supervision (Desmon, Baltimore Sun, 5/21). In 2003, the Accreditation Council for Graduate Medical Education reduced the number of hours residents at teaching hospitals could work weekly from more than 100 hours to 80 hours. In the recent study, which was partially funded by IOM, researchers examined post-2003 literature on resident work hours and patient harm and evaluated it against additional labor costs. The authors concluded that the IOM recommendations "would be costly, and their effectiveness is unknown" (Shishkin, Wall Street Journal, 5/21). Teryl Nuckols, the lead author of the study, said that teaching hospitals would most likely need to hire more residents and experienced physicians to take care of patients, which would likely cost each teaching hospital $3.2 million annually (Baltimore Sun, 5/21). The study was accompanied by an NEJM editorial in which the authors "strongly disagree" with the IOM recommendations, claiming that reducing resident work hours "leads to an increase in the number of handoffs in care, and this increase outweighs the potential benefits of reducing residents" fatigue." The accreditation council said that more research is needed before it decides whether to adopt the IOM recommendations. The council"s decision will be announced in February 2010 (Wall Street Journal, 5/21).
Barts and the London NHS Trust has become the first National Health Service provider in the United Kingdom to offer rapid, oral HIV tests, BBC News reports. Officials hope that the service will increase the number of people who seek testing because requirements of giving blood and waiting for test results are eliminated with the rapid tests. Barts will offer the rapid, oral tests in non-health care settings such as outreach centers. In addition, sexual health workers hope to be able to offer the test in night clubs in the future. About 200 people in Barts clinics have received rapid tests since March, and officials hope to test 250 people monthly. Merle Symonds, the sexual health adviser at the trust, said the message that HIV is a treatable disease has not "filtered through and stigma does remain around HIV, even if it is waning." Lisa Power of the Terrence Higgins Trust -- an HIV/AIDS organization that also offers rapid, oral tests -- said that a major problem surrounding HIV/AIDS in the United Kingdom is that many people are not aware of their status. She added, "Anything we can do to increase the take-up of testing is welcome, and we think what Barts is doing is fantastic."According to BBC News, the United Kingdom has the largest number of people living with HIV in Western Europe, with men who have sex with men accounting for 41% of new cases. BBC News reports that approximately one-third of HIV-positive people in the country are not aware of their status (BBC News, 5/20).
The following highlights efforts that seek to reduce racial and ethnic health disparities.
University of Texas at San Antonio (UTSA) Department of Biology researcher Andrew Tsin stood among an elite group of eye researchers last week when he was named a Silver Fellow in the Association for Research in Vision and Ophthalmology (ARVO)"s inaugural class of fellows. ARVO"s new honor recognizes the professional accomplishments and service of its members as well as their contributions to the association"s advancement.
"Trends in Child Health 1997-2006: Assessing Racial/Ethnic Disparities in Unmet Dental Care Needs," Joint Center for Political and Economic Studies: The issue brief examines disparities in the reporting of unmet dental care needs because of cost over the past 12 months among black, Hispanic and white children younger than age 18. The brief compares the unmet dental care needs among the racial/ethnic groups of children overall and among children of various racial/ethnic groups in families with similar sociodemographic characteristics, such as family type, poverty status and health insurance coverage. Hispanic children are the most likely to have dental care needs that are unmet because of cost, according to the brief. In addition, the brief analyzes several indicators of child health -- including low birthweight, health status, unmet dental care needs, ADHD/ADD diagnosis and asthma diagnosis -- to provide additional details of disparities in child health (Joint Center for Political and Economic Studies, May 2009).
A discovery made by researchers at McGill University and the affiliated Lady Davis Research Institute for Medical Research at Montreal"s Jewish General Hospital offers new hope for the early diagnosis and treatment of Alzheimer"s disease.
Looking for efficient anti-tumor drugs is a hot research area. Chrysin (5,7-dihydroxy flavone), a natural widely-distributed flavonoid, has been reported to have many different biological activities such as anti-oxidant, anti-virus, antidiabetogenic activity and clear anxiolytic effect. However, Chrysin is limited in its clinical application because of its modest absorption in the intestine and rapid in vivo glycosylation. To improve the biological activity of chrysin, a number of its derivatives have been prepared for biological testing. 5-allyl-7-gen-difluoromethylenechrysin (ADFMChR) is one of them.
Today, fifteen new research projects aimed at bringing innovative medicines to market faster have been selected to receive 246 million Euros from the European Commission and the European Federation of Pharmaceutical Industries and Associations (EFPIA), of which the Irish Pharmaceutical Healthcare Association (IPHA) is a member. The projects will foster understanding of health issues such as diabetes, pain, severe asthma and psychiatric disorders while increasing medicine safety. They will also help improve the training of researchers and clinicians involved in medicines development. The projects were chosen following the first call for proposals launched within the Innovative Medicines Initiative (IMI), a public-private partnership - so called Joint Technology Initiative - between the European Commission and the pharmaceutical industry.
A survey among Britain"s 40,000 sufferers from dystonia - a
Mr Secretary General, Madame Director General, Ladies and Gentlemen, we are gathered here today in the shadow of the pandemic influenza threat posed by the Novel A / H1N1 virus.
Only slightly more than half of the 18 million Americans diagnosed with diabetes had their blood sugar, cholesterol, and blood pressure under optimum control in 2006, according to the latest News and Numbers from the Agency for Healthcare Research and Quality.
Responding to the figures contained in Statistics on Alcohol: England 2009, Professor Ian Gilmore, President of the Royal College of Physicians said:
Royal Philips Electronics (NYSE: PHG, AEX: PHI) introduced three new respiratory support devices: the Respironics V60 and V200, and Trilogy100 ventilators. These ventilation solutions are intended to support breathing in the intensive care, sub-acute, and home care settings. As a family of products, the three devices are well-suited to address the ventilation care challenges that clinicians face on a daily basis, such as treating respiratory failure from exacerbations of chronic obstructive pulmonary disease (COPD) while avoiding ventilator-associated pneumonia.
There has been an alarming rise in new cases of the deadliest form of skin cancer in the UK, with binge tanning cited as a main reason, said a
Funding from the Biotechnology and Biological Sciences Research Council (BBSRC) could lead to the development of new and better treatments for broken bones and other orthopaedic problems associated with ageing.
Siblings of cancer victims often feel left out and have nobody to share their grief with. However, the illness may help strengthen the bond between a healthy and a cancer-stricken sibling. This is shown in a doctoral thesis at the Sahlgrenska Academy at University of Gothenburg, Sweden.
For the second year in a row, the American Red Cross is encouraging loyal NASCAR fans to donate blood through the Red Cross by joining Red Cross Racing.
On World No Tobacco Day, The Lung Association is celebrating those who have successfully quit smoking and sharing their success stories in the hopes of motivating others to quit.
Dr Hamish Meldrum, Chairman of BMA Council, has written to the Secretary of State for Health, Alan Johnson, to request that he intervenes to ensure that the UK does not lose further doctors as a result of recent changes to the immigration system. The changes restrict international medical students, who are studying in the UK, from continuing with their medical training beyond the two-year postgraduate Foundation Programme.
A heart muscle protein can replace its missing skeletal muscle counterpart to give mice with myopathy a long and active life, show Nowak et al. The findings were published online on May 25, 2009 (http://www.jcb.org) and will appear in the June 1, 2009 print issue of the Journal of Cell Biology.
Researchers with the Susan G. Komen for the Cure Tissue Bank at the IU Simon Cancer Center will continue their unique work thanks to a second $1 million grant from the Komen organization.
Thank parasites for making some of our immune proteins into the inflammatory defenders they are today, according to a population genetics study that will appear in the June 8 issue of the Journal of Experimental Medicine (online May 25). The study, conducted by a team of researchers in Italy, also suggests that you might blame parasites for sculpting some of those genes into risk factors for intestinal disorders.
Matrox Graphics Inc., the leading manufacturer of specialized graphics solutions, announced that QUBYX has integrated DATACOLOR"s Spyder3 colorimeter into its PerfectLUM medical display calibration software. In addition, the calibration software will also support the Matrox Xenia(tm) Series onboard 13-bit Gamma and Digital Luminance Correction (DLC(tm)) technology. By combining each company"s extensive and high quality solutions, Matrox has created a comprehensive package for the medical display and imaging marketplace that will ultimately save time, money, and improve efficiencies in patient care.
Health and Human Services Secretary Kathleen Sebelius announced today that the Department of Health and Human Services (HHS) is joining the Ad Council and Sesame Workshop, the nonprofit educational organization behind Sesame Street, to launch a national public service advertising campaign designed to encourage American families and children to take steps to protect themselves from the 2009 H1N1 flu virus and continue to practice healthy habits. As part of HHS and the Ad Council"s campaign, Sesame Workshop produced a television PSA featuring Sesame Street"s Elmo and Gordon explaining the importance of healthy habits such as washing your hands, avoid touching your eyes, nose and mouth and sneezing into the bend of your arm.
World renowned virologist Professor Albert Osterhaus told participants at Europe"s largest conference on infectious diseases that the outbreak of influenza A H1N1 is without question the most important event of the past 40 years in human influenza. And he stressed that the current H1N1 threat is a serious one.
ReachMD, which provides medical news and information to healthcare practitioners, is raising its profile with the Continuing Medical Education, or CME, application for the Apple iPhone and iPod touch. This is the first CME application that lets users listen to all ReachMD Continuing Medical Education content, get regular updates on new Continuing Medical Education content and take Continuing Medical Education tests for credit, all from their iPhone or iPod touch.
A family-based prevention program designed to help adolescents avoid substance use and other risky behavior proved especially effective for a group of young teens with a genetic risk factor contributing toward such behavior, according to a new study by researchers at the University of Georgia. The National Institute on Alcohol Abuse and Alcoholism (NIAAA) and the National Institute on Drug Abuse (NIDA), components of the National Institutes of Health, supported the study, which appears in the May/June issue of Child Development.
The National Association of Pediatric Nurse Practitioners (NAPNAP) praises Representative Allyson Schwartz and nearly 100 cosponsors of The Preserving Patient Access to Primary Care Act for their leadership in health care reform. This legislation, which will increase the number of primary care providers and improve patient access to primary care services, is a critical step if we truly are to reform our health care delivery system. Our nation needs leaders like Representative Schwartz to affect real and lasting change in our health care system.
The Society for Prevention Research (SPR) will hold its annual meeting, May 27-29, 2009, at the Hyatt Regency, 400 New Jersey Avenue, NW, Washington, D.C., 20001. The featured stories are:
NewYork-Presbyterian Hospital and Columbia University Medical Center, together with the Cardiovascular Research Foundation (CRF), announced that its landmark study comparing the safety and efficacy of drug-eluting stents and bare-metal stents was published in the May 7 New England Journal of Medicine. The study, HORIZONS-AMI (Harmonizing Outcomes with RevascularIZatiON and Stents in Acute Myocardial Infarction), showed that in heart attack patients undergoing angioplasty, the use of paclitaxel-eluting stents reduces rates of target lesion revascularization (TLR) and binary angiographic restenosis when compared to the use of bare-metal stents after one year.
Restricting carbohydrates, regardless of weight loss, appears to slow the growth of prostate tumors, according to an animal study being published this week by researchers in the Duke Prostate Center.
When a cancer patient and his or her doctor discuss the value of a treatment option, the conversation usually centers on a consideration of the treatment"s medical benefits versus its possible side effects for the patient. Increasingly, however, as the already high costs of cancer care continue to rise, a full view of the patient"s welfare must also take into account the economic impact of the treatment on the patient and his or her family.
Two-thirds of American teenagers have sex by the time they"re 18. A new longitudinal study finds that when adolescents engage in risky sexual activity, fathers respond by increasing their efforts to supervise and monitor their children.
Cancer patients treated with the widely used drug bevacizumab (Avastin) in combination with chemotherapy are at greater risk of life-thereatening gastrointestinal (GI) perforations. This is the conclusion of Shenhong Wu, M.D., Ph.D., Principal Investigator, and colleagues at Stony Brook University Medical Center, in a study published online and in the June print issue of The Lancet Oncology.
Today sees the European launch of the first topical calcineurin inhibitor to be approved for the maintenance treatment of eczema to prevent flares and prolong flare-free intervals. PROTOPIC ointment (tacrolimus monohydrate) is already licensed to treat moderate and severe eczema (atopic dermatitis), often involving the treatment of flares as and when they occur.* It is now also approved for twice-weekly application to previously affected skin to prevent these exacerbations and prolong flare-free periods in PROTOPIC-responsive patients.ò€ Clinical studies have shown that this new approach brings significant benefits with over 40% of patients with moderate to severe eczema remaining flare-free for at least a year.1 Flares are known to place an enormous burden on patients. The International Study of Life with Atopic Eczema (ISOLATE) found that about 55% of these patients worried about the onset of their next exacerbation and that they spent on average over a third of the year (136 days) with their eczema in flare.2
An innovative hand dryer aimed at cutting the risk of healthcare associated infections (HCAIs) has been launched for NHS trusts and healthcare organisations by NHS Supply Chain.
California (USC) have identified a
Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialty biopharmaceutical company, today announced results of a European survey that found a child"s Attention Deficit Hyperactivity Disorder (ADHD) symptoms at school were a key concern for parents, yet outside of school their child"s ADHD also had significant impact on parents" personal time.1 The survey also revealed key findings surrounding parents" role in assessment and treatment for their child.1 Additionally, the survey suggested that informational needs may not be met adequately for these children with ADHD and their families.1 Conducted in partnership with ADHD advocacy groups in four EU countries, the survey analysed parental impressions surrounding the impact of ADHD on their child, themselves and their family, as well as their child"s ADHD treatment plan.
Physicians can now provide potentially safer and more accurate diagnostic procedures with the first and only high-definition endoscopic ultrasound (EUS) needle technology. Cook Medical, the only full-line supplier of endoscopic medical devices, has designed a complete line of high-definition EUS biopsy needles that are up to three-times brighter than others on the market. With the addition of the 19 and 25 gage EchoTip® Ultra with High Definition Fine Needle Aspiration (HDFNA™) needles, the EchoTip Ultra HDFNA represents the next level of precision in EUS, an essential diagnostic tool that yields more accurate images of the gastrointestinal (GI) tract than traditional ultrasound and provides minimally invasive access to areas that are traditionally difficult to reach.
Tackling the very causes of ageing, rather than treating the symptoms in a piecemeal way offers the best prospects for dealing with the diseases and effects of ageing according to a public lecture being given at the Royal Society tonight.
Preliminary results from a double-blind, randomised, multicentre trial among 660 patients with chronic obstructive pulmonary disease (COPD) show that budesonide/formoterol (Symbicort®: AstraZeneca) plus tiotropium (Spiriva™: Boehringer Ingelheim Limited) significantly improves disease control and patients" quality of life.1,2
Research from the National Osteoporosis Society has revealed that almost half (49%)* of young people do not know that there are steps they can take to keep their bones healthy. This knowledge gap puts them at risk of osteoporosis and fractures in later life.
Concerns regarding the H1N1 flu strain or the current global economic recession should not take attention away from the long-term fight against HIV/AIDS, Julio Mantaner, head of the International AIDS Society, said recently, VOA News reports. Mantaner said global health issues need to be "put ... into the proper perspective," adding, "No doubt that ... whatever new flu or any other epidemic that may show up the day after tomorrow ... is something that we need to respond to. But it cannot be at the expense of a proven, established killer" like HIV/AIDS. He said that although it is important to remain vigilant in detecting emerging epidemics and infectious diseases, "we"re (doing) ourselves a very serious disservice" when res are taken away from combating HIV/AIDS and given to "the next new potential epidemic."Mantaner said that although it is "clear that we failed to meet original targets" in the global fight against HIV/AIDS, there has been an increase in the number of HIV-positive people in developing countries receiving antiretroviral treatments from about 500,000 in 2003 to more than three million by the end of 2007. In addition, he said that antiretrovirals are "saving lives of people" and "preserving the social network, the family structure ... that is so severely compromised by HIV and AIDS." Despite this progress, Mantaner said that "[w]e need to recognize more [people] are being infected every day by a factor of nearly two than the number of people accessing antiretroviral therapy."Mantaner urged members of the World Health Assembly -- who recently met in Geneva -- to honor HIV/AIDS commitments, noting that the gains in fighting the pandemic cannot be reversed. He said that he is concerned the global recession, worries over the H1N1 flu and other "competing needs or hypothetical epidemics" could lead to donor nations "losing their interest" in fighting HIV/AIDS. Mantaner said that he is disappointed with President Obama"s recent $63 billion, six-year proposed global health initiative, adding that it falls short of his campaign promises. He said that IAS is asking leaders from the Group of Eight industrialized nations to "refocus their efforts" and "meet their commitments." He warned that if the commitments are not met, "[h]istory is going to judge us very harshly," adding, "We"ve been distracted by the epidemic of the day without recognizing that we have a killer within our midst that we can control" (DeCapua, VOA News, 5/21).
CHICAGO, May 26, 2009 - New data show that nab-paclitaxel (AbraxaneR for Injectable Suspension) prolongs investigator-assessed, median progression-free survival (PFS) by almost seven months versus the highest standard dose of docetaxel in women with metastatic breast cancer.
Coconino County Health Department (CCHD) officials announced today the first case of H1N1 (swine) flu in Coconino County. The Arizona Department of Health Services Lab confirmed that a 24 year-old male from the Navajo Nation has tested positive for the illness. The man went to the Tuba City Regional Health Care Corporation Emergency Department with flu-like symptoms and was tested. He is now recovering from the illness.
A growing number of American children are enrolled in child care and questions remain about how these settings may affect them in both positive and negative ways. A new study published in the May/June 2009 issue of the journal Child Development finds that early interpersonal experiences - center-based child care and parenting - may have independent and lasting developmental effects.
Providing girls in rural Africa with a deworming drug could help reduce the spread of HIV, according to a study recently published in PLoS Neglected Tropical Diseases, the New York Times reports. The drug, called praziquantel, costs about 32 cents per pediatric dose and prevents schistosomiasis, a worm disease that starts as a urinary tract infection. If untreated, schistosomiasis can lead to female genital sores that can facilitate HIV infection. Because the drug can kill the worms but cannot cure genital sores, girls should be protected before they reach sexual maturity, according to the Times. "For this relatively small investment, the reproductive health of young women would be improved," the authors from the Sabin Vaccine Institute, Imperial College London and Oslo University wrote, adding that "there is a reasonable chance that HIV/AIDS transmission can be reduced." There are about 207 million schistosomiasis cases worldwide, 90% of which occur in Africa, where humans are exposed usually through snail-infested water. According to a pilot program conducted in Burkina Faso, all 70 million cases among young children in Africa could be treated for $22 million, and repeating universal treatment every two years for 10 years would cost $112 million (McNeil, New York Times, 5/26).
"The most lamentable and heart-breaking dimension of multilateralism" is the "absence of any serious focus on gender throughout" the United Nations system, Stephen Lewis, founder of AIDS-Free World, writes in a London Independent opinion piece. He adds, "I can cite chapter and verse, but let me start by telling you that whether it is poverty alleviation, or HIV and AIDS, or sexual violence and conflict, the whole panoply of discrimination visited on women around the world, particularly in developing countries, the U.N."s agencies and the Secretariat have been profoundly delinquent in their response."According to Lewis, the "struggle for gender equality has become the most important struggle on the planet; the continuing marginalization of 52% of the world"s population is simply unacceptable." He adds, "So we"re now engaged in an effort to create a new international agency for women, a fascinating undertaking that I hope will engage" governments. "Nothing approximates the possibility of finally having a vehicle that would give voice and res and support to the struggles of women around the world," Lewis writes, adding, "Everyone knows what"s happening in these areas about women"s vulnerability but there is never a consistent voice to bring it to the attention of the world community, to continue to hammer it home, to demand action from government." He concludes, "So the emergence and creation of a women"s agency I think would be a godsend internationally and would overcome the record of the United Nations on gender" (Lewis, Independent, 5/22).
Irving A. Cohen, MD, MPH, will be at Book Expo America 2009, Booth 5065, May 29-31, to discuss his new book "Dr. Cohen"s Guide to the New Hippocratic Diet™: How to Really Lose Weight and Beat the Obesity Epidemic" It teaches dieters how to lose weight easily and naturally despite having failed before.
A team of researchers has found an association between breast cancer survival and two proteins that, when present in the blood in high levels, are indicators of inflammation. Using data from the Health, Eating, Activity and Lifestyle (HEAL) study sponsored by the National Cancer Institute, part of the National Institutes of Health, the researchers found that breast cancer patients with elevated levels of C-reactive protein (CRP) and serum amyloid A (SAA) were approximately two to three times more likely to die sooner or have their cancer return than those patients who had lower levels of these proteins, regardless of the patient"s age, tumor stage, race, body mass index, or history of previous cardiovascular issues. The results of this study were published online, May 26, 2009, in the Journal of Clinical Oncology.
Despite the well-known benefits of having a lifestyle that includes physical activity, eating a diet high in fruits and vegetables, maintaining a healthy weight, moderate alcohol use and not smoking, only a small proportion of adults follow this healthy lifestyle pattern, and in fact, the numbers are declining, according to an article published in the June 2009 issue of The American Journal of Medicine. Lifestyle choices are associated with the risk of cardiovascular disease as well as diabetes.
An international team of scientists studying a rare genetic disease discovered that a bundle of proteins with the long-established function of keeping chromosomes together also plays an important role in regulating genes in humans.
A Senior Lecturer from Canterbury Christ Church University has been awarded Fellowship of the Institute of Healthcare Management (IHM) at a ceremony on Thursday 14th May.
A new study found that compared with two decades ago, fewer Americans are following a healthy lifestyle. This is despite the mounting evidence
Medical students and teaching staff have welcomed the Review & Modernisation of Supplement for Undergraduate Medical and Dental Education (SUMDE) consultation, which was undertaken by the DHSSPS.
Several newspapers on Wednesday included editorials and opinion pieces on President Obama"s nomination of Judge Sonia Sotomayor to the Supreme Court. Summaries appear below. ~New York Times: Obama "seems to have made an inspired choice" in selecting Sotomayor as his nominee because she "has an impressive judicial record, a stellar academic background and a compelling life story," a Times editorial states. According to the editorial, "Based on what we know now, the Senate should confirm her so she can join the court when it begins its new term in October." The editorial notes that, "Conservative activists have already begun trying to paint Judge Sotomayor as a liberal ideologue, but her carefully reasoned, fact-based decisions indicate otherwise." The editorial continues, "If Judge Sotomayor joins the court, it will be a special point of pride for Hispanic-Americans," and "will also bring the paltry number of female justices back to two." It adds, "Judge Sotomayor, though, is more than just a distinguished member of two underrepresented groups. She is an accomplished lawyer and judge, who could become an extraordinary Supreme Court Justice" (New York Times, 5/27).~Gerard Magliocca, New York Times: In addition to sharing Obama"s "experience and intellect," Sotomayor "also mirror"s the president"s measured temperament," Magliocca, a law professor at Indiana University, writes in a Times opinion piece. Magliocca writes that he has known Sotomayor for 13 years and notes that although he is a conservative and has at times been "at odds with" Sotomayor professionally, he does not dispute her qualifications. According to Magliocca, "For those of us who think that intellectual rigor and fairness are the crucial factors" to be a Supreme Court justice, "no matter which party the president hails from, there is no question that Judge Sotomayor should be confirmed" (Magliocca, New York Times, 5/27).~USA Today: Upon hearing that Sotomayor was Obama"s nominee, Republican critics "quickly insisted that the Senate assure itself that Sotomayor would not make rulings based on her "personal politics, feelings and preferences,"" a USA Today editorial states. According to the editorial, "To some extent, the entire argument is overblown. People inevitably are the product of their experiences, and they can hardly shed their history and character at the courthouse door." The editorial continues, "That is why the court is enriched by having an eclectic mix of justices who can bring differing perspectives to bear on the case at hand." The editorial concludes, "Sotomayor"s education and experience make her far more than a political twofer who allowed Obama to check the "female" and "Hispanic" boxes. But there"s a limit to the application of empathy and heritage to the law, and her confirmation hearings will be an opportunity for her to spell out exactly where she believes that line falls," (USA Today, 5/27).~ Steven Waldman, Wall Street Journal: "Everyone seems to assume" that Supreme Court nominee Sonia Sotomayor is "ardently for abortion rights," but there is "stunningly little information about her abortion views -- and what we do know hardly paints her as a pro-choice activist," Waldman, president and editor-in-chief of Beliefnet.com and author of "Founding Faith," writes in a Journal opinion piece. He continues that Sotomayor has ruled only on three cases "indirectly related to abortion," and each time ruled in a way preferred by abortion-rights opponents, "albeit for reasons unrelated to the merits of abortion." Although Sotomayor"s decisions in the cases were related "to matters of constitutional law and criminal procedure, ... at a minimum, it showed that whatever her abortion views, it didn"t produce some powerful inclination against the pro-life position," according to Waldman. "Now all of this might not mean anything. She may prove to be a strong advocate of Roe v. Wade. But it"s telling that the abortion interest groups took sides without knowing anything about her abortion
Quality of care is not linked to the cost of care, according to a study published last week on the Web site of the journal Health Affairs, CQ HealthBeat reports. For the study, researchers from Dartmouth College and Harvard University analyzed the health care bills of chronically ill Medicare beneficiaries in their last two years of life who received end-of-life care from 2,172 unidentified hospitals. The patients had one of three common conditions: heart attack, pneumonia or congestive heart failure. The study -- sponsored by the National Institute on Aging -- looked at common quality indicators at a hospital-by-hospital level instead of regional level (Norman, CQ HealthBeat, 5/22). Researchers compared the data with some of the quality measures reported on the HHS Hospital Compare Web site (Goldstein, "Health Blog," Wall Street Journal, 5/21). The study found that among the one-fifth of hospitals that spent the least, the cost of end-of-life care was $16,059 on average. In comparison, the cost of end-of-life care at the top 20% of highest-spending hospitals was $34,742 on average. The study also found no link -- or even evidence against a link -- between spending and the quality indicators. The researchers noted that the results might be skewed because the quality indicators they used might penalize hospitals that treat sicker patients. In addition, the study used process-of-care measures instead of patient outcomes. According to CQ HealthBeat, the findings of the study could have an effect on the debate over health care reform legislation because lawmakers and President Obama both have said that a reform plan must be able to control costs and expand access to high-quality, affordable health care (CQ HealthBeat, 5/22).
Nearly 30 years after the emergence of HIV/AIDS, the global health community must develop new strategies to curb the spread of the disease in sub-Saharan Africa, some experts said Tuesday ahead of the Global Citizens Summit for Social Mobilization to End AIDS in Nairobi, Kenya, AFP/Google.com reports. The advocates also stressed the need for innovative approaches to health financing as international donors shift their attention toward other issues and as the ongoing economic downturn threatens fundraising prospects. The conference, which opens Wednesday, includes participants from 32 countries, primarily in Africa.According to Wasai Jacob Nanjakululu of Oxfam, about 90% of HIV-positive people are unaware of their status and 70% of people in need of treatment are not accessing medical care. Leonard Okello, an HIV/AIDS specialist with ActionAid International, added that the global health community is "far from winning the struggle against" HIV/AIDS. Okello said the conference will examine the shortcomings of earlier HIV/AIDS policies and explore new methods to address the disease. "There are a lot of res in HIV/AIDS programs but not much of that reaches the community," Okello said, asking, "What is it that we should radically change?" (AFP/Google.com, 5/26). According to IRIN/PlusNews, conference participants also plan to discuss "people-centered" approaches to combating HIV/AIDS at the Nairobi meeting. ActionAid Report Calls For Improvements in Basic Health Care To Address HIV/AIDS
Researchers at Roswell Park Cancer Institute (RPCI) in Buffalo, New York, are strongly advocating a national discussion about the need to vaccinate both young men and women against HPV 16 to prevent head & neck cancers. The call comes amid growing evidence that certain cancers of the head and neck are strongly linked to HPV 16, a specific strain of the human papillomavirus (HPV) that is one of the most common sexually transmitted diseases in the United States. It is estimated that approximately 70% of Americans, both men and women, will be infected with HPV at some point in their lives.
A Dream Team of leading cancer researchers will accelerate development of drugs to attack a mutated molecular pathway that fuels endometrial, breast and ovarian cancers, funded by a three-year $15 million grant awarded today by Stand Up To Cancer.
As part of its Centennial Celebration and Conference, Mental Health America-in partnership with the District of Columbia Department of Mental Health-will hold a dedication ceremony on June 10 at 10 a.m. for a memorial planned on the grounds of Saint Elizabeths Hospital for hundreds of thousands of patients who were buried, many with unmarked graves, at state psychiatric hospitals nationwide.
Z-Cube Srl, the corporate venture arm of Zambon Company SpA, and Yissum Research Development Company Ltd., the technology transfer company of the Hebrew University of Jerusalem, announced today that they have entered into a license agreement for Z-Cube to develop and commercialize an innovative nanotechnology drug delivery system for the treatment of pain. The technology was invented by Professor Elka Touitou from the Department of Pharmaceutics, Faculty of Medicine, at the Hebrew University of Jerusalem.
Our brain is wired to identify gender based on facial cues and coloring, according to a new study published in the Journal of Vision. Psychology Professor Frç©dç©ric Gosselin and his Universitç© de Montrç©al team found the luminescence of the eyebrow and mouth region is vital in rapid gender discrimination.
For thousands of years ginger has been treasured for its reputed health benefits, in particular for treating digestive problems including nausea.
Lessons learned at the Canadian-run military hospital in Kandahar, Afghanistan could help surgeons prepare for civilian disasters, according to a London, Ontario physician who has served two tours at the hospital. Dr. Vivian McAlister is a professor in the Department of Surgery at the Schulich School of Medicine & Dentistry at The University of Western Ontario and a general surgeon at the London Health Sciences Centre. He spent two months working at the Kandahar hospital in 2007 as a civilian surgeon before joining the Canadian Forces and doing a second tour at the hospital this past winter.
Scientists at the Medical Research Council Laboratory of Molecular Biology uncover how an important cancer gene, BRCA1, works by increasing the accuracy with which broken DNA is repaired. Women who inherit a faulty version of the BRCA1 gene are at a higher risk of developing breast or ovarian cancer.
The Senate Finance Committee on Thursday will meet to discuss the inclusion of a public insurance plan in its health care reform legislation, the Des Moines Register reports (Beaumont, Des Moines Register, 5/14). Supporters of the public plan say it would allow middle-income workers a choice between their employer coverage and coverage offered by the government. The insurance industry and Republican lawmakers oppose such a plan.The Finance Committee will consider a plan similar to Medicare but that would feature slightly higher reimbursement rates for providers. The plan would either be operated by the government or government-contracted private firms. Another option would allow each state to develop and oversee its own public coverage plan. The committee also will consider a proposal from Sen. Charles Schumer (D-N.Y.) that would allow a new public plan to compete with private insurers by requiring that the public plan be financed by premiums rather than tax dollars, that it follow the same solvency rules that apply to private firms and that it keep a reserve fund to cover liabilities. Schumer"s plan also would allow doctors and hospitals the choice of participating. The public plan also would be required to follow the same consumer protection rules as private firms (Alonso-Zaldivar/Werner, AP/Contra Costa Times, 5/14). The panel also is expected to discuss employer or individual mandates (Edney, CongressDaily, 5/14).Committee ranking member Chuck Grassley (R-Iowa), who has said he believes a public plan would eventually eliminate private insurance and force U.S. residents out of their employer-sponsored plans, said the committee meeting will reveal the likelihood of Republicans uniting against a public option. "We will have an idea how controversial it is and how strong people feel about it on both sides," Grassley said. He added, "I think before I would write it off completely, I would want to look at what those possible compromises are" (Des Moines Register, 5/14). House Energy and Commerce Committee
A new instrument for improving patient understanding and acceptance of long-acting injectable antipsychotic therapy (LAT) has been published in the April edition of Psychiatry 2009.1 This novel, psychosocial approach encompasses Goal setting, Action planning, Initiating treatment, and Nurturing motivation (GAIN) through the use of a clinical discussion tool.
Walsall Hospitals NHS Trust has "gone-live" with Horizon Enterprise Visibility; a visual control system designed specifically for hospitals, from healthcare IT solutions and services specialists, McKesson. Via real-time access to patient information, Walsall will be using Horizon Enterprise Visibility to improve re efficiency and bed utilisation to reduce costs and improve the quality of patient care.